List of Famous people who died at 46

Maurizio Gucci (September 26, 1948 – March 27, 1995) was an Italian businessman, and the one-time head of the Gucci fashion house. He was the son of Rodolfo Gucci, and grandson of Guccio Gucci.

Aileen Carol "Lee" Wuornos was an American serial killer and sex worker who murdered seven men in Florida in 1989 and 1990 by shooting them at point-blank range. Wuornos claimed that her victims had either raped or attempted to rape her while they were soliciting sex from her, and that all of the homicides were committed in self-defense. She was sentenced to death for six of the murders and was executed by lethal injection on October 9, 2002.

Joseph Robinette "Beau" Biden III was an American politician, lawyer, and officer in the Army Judge Advocate General's Corps from Wilmington, Delaware. He was the eldest of three children from the marriage of U.S. President Joe Biden and his first wife, Neilia Hunter Biden. He served as the 44th Attorney General of Delaware and was a Major in the Delaware Army National Guard.

George Perry Floyd Jr. was an African American man killed during an arrest after a store clerk alleged he had passed a counterfeit $20 bill in Minneapolis. Derek Chauvin, one of four police officers who arrived on the scene, knelt on Floyd's neck for a period initially reported to be 8 minutes and 46 seconds. After his death, protests against police brutality, especially toward black people, quickly spread across the United States and internationally.

Dolores Mary Eileen O'Riordan was an Irish musician, singer, and songwriter. She was best known as the lead vocalist and lyricist for the alternative rock band the Cranberries. O'Riordan had one of the most recognizable female voices in rock in the 1990s. She was known for her lilting mezzo-soprano voice, her signature yodel, her emphasised use of keening, and her strong Limerick accent. With the Cranberries, she is regarded to have written "some of the most seminal songs in music history".

Adler Berriman "Barry" Seal was a commercial airline pilot who became a major drug smuggler for the Medellín Cartel. When Seal was convicted of smuggling charges, he became an informant for the Drug Enforcement Administration and testified in several major drug trials. He was murdered in 1986 by contract killers hired by the cartel.

Philip Seymour Hoffman was an American actor, director, and producer. Known for playing distinctive supporting and character roles, he acted in many films from the early 1990s until his death in 2014. He is widely considered to be one of the greatest actors of his generation.

André René Roussimoff, better known as André the Giant, was a French professional wrestler and actor.

Chyna was an American professional wrestler, glamour model, pornographic actress, author and bodybuilder. She first rose to prominence in the World Wrestling Federation in 1997, where she was billed as the "Ninth Wonder of the World". A founding member of the stable D-Generation X as the promotion's first female enforcer, she held the WWF Intercontinental Championship twice and the WWF Women's Championship once. She was also the first woman to participate in the Royal Rumble match and King of the Ring tournament, as well as to become number one contender to the WWF Championship. With singles victories over several prominent male wrestlers – including multiple-time world champions Triple H, Kurt Angle, Chris Jericho, and Jeff Jarrett – Chyna left what WWE called "a lasting legacy as the most dominant female competitor of all time". After leaving the WWF in 2001, Chyna wrestled sporadically, with New Japan Pro Wrestling (NJPW) in 2002 and Total Nonstop Action Wrestling (TNA) in 2011. The latter was her final appearance in a wrestling ring.

Marsha P. Johnson, born and also known as Malcolm Michaels Jr., was an American gay liberation activist and self-identified drag queen. Known as an outspoken advocate for gay rights, Johnson was one of the prominent figures in the Stonewall uprising of 1969. Johnson was a founding member of the Gay Liberation Front and co-founded the radical activist group Street Transvestite Action Revolutionaries (S.T.A.R.), alongside close friend Sylvia Rivera. Johnson was also a popular figure in New York City's gay and art scene, modeling for Andy Warhol, and performing onstage with the drag performance troupe Hot Peaches. Johnson was known as the "mayor of Christopher Street" due to being a welcoming presence in the streets of Greenwich Village. From 1987 through 1992, Johnson was an AIDS activist with ACT UP.