List of Famous people born in Valparaíso Region, Chile

Julio Sergio Videla Cabezas was a Chilean radio host and television personality. Videla began his rise to Latin American fame in 1973, when he was the last person to broadcast on Radio Magallanes before the coup.

Mauricio Hernández Norambuena is a former guerrilla fighter and commander of the political-military organization Manuel Rodríguez Patriotic Front where he performed some of the main military and logistical functions within the group, thus becoming one of its main leaders. During his stay at the FPMR, he acquired the nickname "Commander Ramiro", with which he is still widely known today.

David Marcelo Pizarro Cortés is a retired Chilean former professional footballer who last played as a midfielder for Chilean Primera División club Universidad de Chile. He is usually deployed as a central midfielder, although he can also operate in a holding role in front of the back-line, in a more attacking position in the hole behind the strikers, or even as a deep-lying playmaker. An intelligent and technically gifted player, who possesses significant physical strength in spite of his diminutive stature, and an ability to dictate play in midfield, Pizarro is known in particular for his vision, range of passing, dribbling skills, and ability from set pieces.

Mario Alfredo Salas Saieg is a former Chilean football midfielder. He earned five caps for the Chile national team, scoring no goals between 1993 and 1997. Salas made his debut on 1993-09-08 in a friendly match against Spain in Alicante. He started his managerial career at Barnechea in 2009. In 2011, he wins the Tercera División de Chile title and the promotion to Primera B. In 2012, he was appointed as head coach of the Chile U20 National Football Team after the resignation of Fernando Carvallo.

Adriana Margarita Olguín Büche was a Chilean lawyer and politician. She was the Minister of Justice during the rule of Gabriel González Videla, making Olguín the first female Latin American minister of Chile.

Catalina Edwards is a Chilean journalist. She is currently a news anchor on Ahora Noticias and a panelist on Mucho Gusto, both television shows on the Mega channel.

Tomás Enrique Araya Díaz is a Chilean-American musician, best known as the vocalist and bassist of American thrash metal band Slayer. Araya is ranked fifty-eighth by Hit Parader on their list of the 100 Greatest Metal Vocalists of All Time.

Manuel José Ossandón Irarrázabal, colloquially "Cote Ossandón", is an agricultural technician and a senator of Chile for the 8th Senatorial District. He was elected during the parliamentarian elections of 2013, for the period 2014–2022. Member of Chilean center-right party Renovación Nacional (RN). He renounced in July 2016.

Eugenio Esteban Mena Reveco is a Chilean professional footballer who plays as a left back for Argentinian club Racing Club and the Chile national team.

Artur Manfred Max Neef was a Chilean economist of German descent. Max-Neef was born in Valparaíso, Chile. He started his career as a professor of economics at the University of California, Berkeley in the early 1960s. He was known for his taxonomy of fundamental human needs and human scale development. In 1983, he was awarded the Right Livelihood Award for "revitalising small and medium-sized communities through 'Barefoot Economics'."