List of Famous people born in Santiago Metropolitan Region, Chile

Solange Lackington Gangas is a Chilean actress, director and playwright of film, theater and television. She studied theater at the School of Theater of the Pontifical Catholic University of Chile. At just 20 years old, she made her debut on television, acting in telenovelas such as La torre 10 (1984) and Bellas y audaces (1988), alongside figures such as Sonia Viveros, Lucy Salgado and Luis Alarcón. During this period, she collaborated with the producer Sonia Fuchs in the Dramatic Area of Televisión Nacional de Chile. She achieved great popularity by playing Estrellita on the daily series Los Venegas. However, her consecration was due to her joining the Dramatic Area of Channel 13, acting in telenovelas such as Sabor a ti, Piel canela, Machos and Brujas. In this period, she achieved a season of great awards for her work, including Apes Awards and Altazor Awards. In 2017, she assumed the title role in Edward Franklin Albee's play Who's Afraid of Virginia Woolf ?. Her performance in this play earned her positive reviews. A year later, she played Gabriela Mistral in Andrés Kalawski's Mistral, Gabriela, 1945.

Josepablo Monreal Villablanca is a Chilean professional footballer who plays as striker in Cobreloa. He is in progress to obtain the German Passport.

Maite Alberdi Soto is a Chilean film producer, director, documentarian, screenwriter, and film critic. Her most recent film The Mole Agent (2020) was an Academy Awards nominee for Best Documentary and a contender for Best International Feature. The film is also a nominee at the Goya Awards for Best Iberoamerican Film. Maite is the founder of Micromundo Producciones.

Guillermo "Mito" Pereira Hinke is a Chilean professional golfer who plays on the PGA Tour, having earned an automatic three-win promotion from the 2020–21 Korn Ferry Tour.

Julio Humberto Gonzalo Benito Jung del Favero is a Chilean actor.

Rodrigo Javier Hinzpeter Kirberg is a Chilean lawyer and politician. He was one of the founders of National Renewal, a center-right political party. He was appointed Interior Minister on 11 March 2010 by President of Chile Sebastián Piñera. On 5 November 2012 he was appointed Defense Minister and his term ended on 11 March 2014.

Carmen Hertz Cádiz is a Chilean Communist Party politician and lawyer who participated in various institutions for the protection of human rights that arose as a result of the systematic violations committed during the dictatorship headed by Augusto Pinochet from 1973 to 1990. She worked with the Vicariate of Solidarity, the Social Aid Foundation of Christian Churches (FASIC), the National Corporation for Reparation and Reconciliation, and the Ministry of the Interior's Human Rights Program. She became the human rights director of the Ministry of Foreign Affairs after Chile's transition to democracy, and was elected to the Chamber of Deputies in 2018.

Marcelo Iván Allende Bravo is a Chilean footballer who plays as an attacking midfielder for Torque and Chile's national U-20 team. Allende captained Chile at the 2015 FIFA U-17 World Cup and was the team's top goalscorer and is considered one of the top youth prospects in Chilean football.

Jaime Andrés Valdés Zapata is a Chilean footballer who plays for Chilean Segunda División side San Antonio Unido. He usually plays as midfielder. Valdés was member of his national under-20 national team in the 2001 FIFA World Youth Championship and has represented three times the senior team between 2001 and 2010.

Amaya Forch Barry is a Chilean actress and pop singer known for making appearances on various Chilean television programs.