List of Famous people born in Pennsylvania, United States of America

David G. Heckel is an American entomologist.

Jane Winton was an American film actress, dancer, opera soprano, writer, and painter.

John Patrick Foley was an American cardinal of the Roman Catholic Church. From 2007 until 2011, he was Grand Master of the Equestrian Order of the Holy Sepulchre of Jerusalem, an order of knighthood under papal protection, having previously served as President of the Pontifical Council for Social Communications from 1984 to 2007. He was elevated to the cardinalate in 2007. He provided the commentary for the American television viewers of the Christmas Midnight Mass from St Peter's Basilica, Rome. However, in 2009, he retired from that role after 25 years. The commentary was taken over by Monsignor Thomas Powers of the Diocese of Bridgeport, Connecticut, an official in the Congregation for Bishops.

Emmaline Henry was an American actress best known for playing Amanda Bellows, the wife of Dr. Alfred Bellows, on the hit 1960s situation comedy I Dream of Jeannie.

Squire Maugridge Boone Jr., Squire Boone Jr., or Squire Boone was an American frontiersman, longhunter, soldier, city planner, politician, land locator, judge, politician, gunsmith, miller, and brother of Daniel Boone. In 1780, he founded the first settlement in Shelby County, Kentucky. The tenth of eleven children, Squire Boone was born to Squire Boone Sr. and his wife Sarah (Morgan) Boone in Berks County, Pennsylvania, at the Daniel Boone Homestead. Although overshadowed by his famous brother, Squire Boone was well known in his day.

Grayson Hall was an American television, film and stage actress. She was widely regarded for her avant-garde theatrical performances from the 1960s to the 1980s. Hall was nominated for an Academy Award for Best Supporting Actress and a Golden Globe Award for the John Huston film The Night of the Iguana (1964).

Mary Boone is an American art dealer and gallerist, and the owner and director of the Mary Boone Gallery. She played an important role in the New York art market of the 1980s. Her first two artists, Julian Schnabel and David Salle, became internationally known, and in 1982 she had a cover story on New York magazine tagged "The New Queen of the Art Scene." The Mary Boone Gallery has represented artists including Jean-Michel Basquiat, Barbara Kruger, Eric Fischl, Ross Bleckner, and Brice Marden. Originally based in SoHo, Boone operated two galleries, one in midtown on Fifth Avenue, the other in Chelsea. Following her 2019 conviction and sentencing to 30 months in prison for tax evasion, she indicated the intention to close both galleries.

David Russell Edgerton Jr. was an American entrepreneur and co-founder of the Burger King Corporation, in what would become the second largest burger chain after McDonald's. After serving as a manager of another restaurant, Howard Johnson's, on March 1, 1954 he opened a franchise outlet of the restaurant chain Insta Burger King in Miami, Florida. On June 1 of the same year, he met fellow restaurateur James McLamore and the two founded the Burger King Corporation. After leaving Burger King, he went on to start Bodega, a steakhouse restaurant.

Marion Burnside Randall, who acted under the name Sue Randall, was an American actress best known for her role as the kindly Miss Alice Landers, Theodore "Beaver" Cleaver's elementary school teacher in the CBS and ABC sitcom Leave It to Beaver.

Ellen Rose Albertini Dow was an American film and television character actress and drama coach. She portrayed feisty old ladies and is best known as the rapping grandmother Rosie in The Wedding Singer (1998), performing "Rapper's Delight". Dow's other film roles include elderly lady Mary Cleary who "outs" her grandson in Wedding Crashers, Disco Dottie in 54, the recipient of Christopher Lloyd's character's slapstick in Radioland Murders and a choir nun in Sister Act. She was best known to small screen audiences for her guest appearances on sitcoms The Golden Girls and Will & Grace.