List of Famous people born in Castile and León, Spain

Alfonso de Santa María de Cartagena was a Jewish convert to Christianity, a Roman Catholic bishop, diplomat, historian and writer of pre-Renaissance Spain.

José María Martín de Herrera y de la Iglesia was a long-serving cardinal in the Roman Catholic Church in the early years of the twentieth century. Unusually, he served as archbishop of dioceses in more than one different country, being both archbishop of Santiago de Cuba and of Santiago de Compostela during his career in the Church.

Julio Jiménez Muñoz was a Spanish professional road racing cyclist.

Jesús Caldera Sánchez-Capitán is a Spanish socialist politician. He holds degrees in political science and sociology from the Complutense University of Madrid and a law degree from UNED.He was Minister of Labor during the eighth legislature of the Spanish government (2008-2011).

Alberto Prada Vega is a Spanish professional footballer who plays for Austrian club SK Vorwärts Steyr as a left back.

Faustino Rupérez Rincón is a retired Spanish professional road racing cyclist who raced between 1979 and 1985. Ruperez is most famous for capturing the overall title at the 1980 Vuelta a España.