List of Famous people who born in 1946

Robert Xavier Rodríguez is an American classical composer, best known for his eight operas and his works for children.

Loleatta Holloway was an American singer, mainly known for disco songs such as "Hit and Run" and "Love Sensation". In December 2016, Billboard named her the 95th most successful dance artist of all time. According to the Independent, Holloway had "undoubtedly the most sampled female voice in popular music" that was used in house and dance tracks.

Tak Wah Mak, is a Canadian medical researcher, geneticist, oncologist, and biochemist. He first became widely known for his discovery of the T-cell receptor in 1983 and pioneering work in the genetics of immunology. In 1995, Mak published a landmark paper on the discovery of the function of the immune checkpoint protein CTLA-4, thus opening the path for immunotherapy/checkpoint inhibitors as a means of cancer treatment. Mak is also the founder of Agios Pharmaceuticals, whose lead compound, IDHIFA®, was approved by the FDA for acute myeloid leukemia in August 2017, becoming the first drug specifically targeting cancer metabolism to be used for cancer treatment. He has worked in a variety of areas including biochemistry, immunology, and cancer genetics.

Tan Aik Huang is a retired Malaysian Chinese badminton player noted for his superb footwork and patience. He is the elder brother of Tan Aik Mong.

Dame Calliopa Pearlette Louisy was the Governor-General of Saint Lucia from 1997 to 2017. She was the first woman to hold this office, into which she was sworn on 19 September 1997, and resigned from on 31 December 2017.

Àngel Casas i Mas was a Spanish journalist and writer.

Robin Berry Janvrin, Baron Janvrin, is a British courtier who was Private Secretary to Elizabeth II from February 1999 to September 2007.