List of Famous people born in South Carolina, United States of America

Rosalie Anderson "Andie" MacDowell is an American actress and fashion model. She made her film debut in 1984's Greystoke: The Legend of Tarzan, Lord of the Apes, before receiving critical acclaim for her role in Sex, Lies, and Videotape (1989), for which she won Independent Spirit Award for Best Female Lead and was nominated for a Golden Globe Award for Best Actress – Motion Picture Drama. She also received Golden Globe Award nominations for her performances in Green Card (1990) and Four Weddings and a Funeral (1994).

Chadwick Aaron Boseman was an American actor and playwright. After studying directing at Howard University, he became prominent in theater, winning a Drama League Directing Fellowship and an acting AUDELCO, and being nominated for a Jeff Award as a playwright for Deep Azure. Transitioning to the screen, he landed his first major role as a series regular on Persons Unknown in 2010, and his breakthrough performance came in 2013 as baseball player Jackie Robinson in the biographical film 42. He continued to portray historical figures, starring in Get on Up (2014) as singer James Brown and Marshall (2017) as Supreme Court Justice Thurgood Marshall.

Kelsey Asbille Chow is an American actress. She is known for her role as Mikayla in the Disney XD sitcom Pair of Kings. From 2005 to 2009, she had a recurring role as Gigi Silveri on the drama One Tree Hill. She portrayed Tracy Stewart in MTV's Teen Wolf from 2015–2016.

Nimrata Nikki Haley is an American politician, diplomat, businesswoman and author who served as the 116th governor of South Carolina from 2011 to 2017 and as the 29th United States ambassador to the United Nations from 2017 to 2018.

James Edward Costa, known by his stage name Jamie Costa, is an American actor, director, producer, writer, voice actor, filmmaker, comedian, and impressionist who is best known for the likeness of Robin Williams and impressions of many characters.

Tyshun Raequan "Deebo" Samuel is an American football wide receiver for the San Francisco 49ers of the National Football League (NFL). He played college football at South Carolina and was drafted by the 49ers in the second round of the 2019 NFL Draft.

Dustin Hunter Johnson is an American professional golfer who plays on the PGA Tour. He has won two major championships, the 2016 U.S. Open at Oakmont Country Club with a 4-under-par score of 276 and the 2020 Masters Tournament with a record score of 268, 20-under-par. He had previously finished in a tie for second at both the 2011 Open Championship and the 2015 U.S. Open. He has six World Golf Championships victories, with only Tiger Woods having won more, and he is the first player to win each of the four World Golf Championship events.

Hunter Renfrow is an American football wide receiver and return specialist for the Las Vegas Raiders of the National Football League (NFL). He played college football at Clemson.

Viola Davis is an American actress and producer. Having won an Academy Award, a Primetime Emmy Award, and two Tony Awards, she is the first African-American to achieve the "Triple Crown of Acting". Time magazine named her one of the 100 most influential people in the world in 2012 and 2017. In 2017 she received a star on the Hollywood Walk of Fame. In 2020, The New York Times ranked Davis ninth on its list of "The 25 Greatest Actors of the 21st Century".

Lindsey Olin Graham is an American politician serving as the senior United States Senator from South Carolina, a seat he has held since 2003. A member of the Republican Party, Graham served as chairman of the Senate Committee on the Judiciary from 2019 to 2021.