List of Famous people born in South Carolina, United States of America

Rosalie Anderson "Andie" MacDowell is an American actress and fashion model. She made her film debut in 1984's Greystoke: The Legend of Tarzan, Lord of the Apes, before receiving critical acclaim for her role in Sex, Lies, and Videotape (1989), for which she won Independent Spirit Award for Best Female Lead and was nominated for a Golden Globe Award for Best Actress – Motion Picture Drama. She also received Golden Globe Award nominations for her performances in Green Card (1990) and Four Weddings and a Funeral (1994).

Chadwick Aaron Boseman was an American actor and playwright. After studying directing at Howard University, he became prominent in theater, winning a Drama League Directing Fellowship and an acting AUDELCO, and being nominated for a Jeff Award as a playwright for Deep Azure. Transitioning to the screen, he landed his first major role as a series regular on Persons Unknown in 2010, and his breakthrough performance came in 2013 as baseball player Jackie Robinson in the biographical film 42. He continued to portray historical figures, starring in Get on Up (2014) as singer James Brown and Marshall (2017) as Supreme Court Justice Thurgood Marshall.

Kelsey Asbille Chow is an American actress. She is known for her role as Mikayla in the Disney XD sitcom Pair of Kings. From 2005 to 2009, she had a recurring role as Gigi Silveri on the drama One Tree Hill. She portrayed Tracy Stewart in MTV's Teen Wolf from 2015–2016.

Nimrata Nikki Haley is an American politician, diplomat, businesswoman and author who served as the 116th governor of South Carolina from 2011 to 2017 and as the 29th United States ambassador to the United Nations from 2017 to 2018.

James Edward Costa, known by his stage name Jamie Costa, is an American actor, director, producer, writer, voice actor, filmmaker, comedian, and impressionist who is best known for the likeness of Robin Williams and impressions of many characters.

Tyshun Raequan "Deebo" Samuel is an American football wide receiver for the San Francisco 49ers of the National Football League (NFL). He played college football at South Carolina and was drafted by the 49ers in the second round of the 2019 NFL Draft.

Dustin Hunter Johnson is an American professional golfer who plays on the PGA Tour. He has won two major championships, the 2016 U.S. Open at Oakmont Country Club with a 4-under-par score of 276 and the 2020 Masters Tournament with a record score of 268, 20-under-par. He had previously finished in a tie for second at both the 2011 Open Championship and the 2015 U.S. Open. He has six World Golf Championships victories, with only Tiger Woods having won more, and he is the first player to win each of the four World Golf Championship events.

Hunter Renfrow is an American football wide receiver and return specialist for the Las Vegas Raiders of the National Football League (NFL). He played college football at Clemson.

Viola Davis is an American actress and producer. Having won an Academy Award, a Primetime Emmy Award, and two Tony Awards, she is the first African-American to achieve the "Triple Crown of Acting". Time magazine named her one of the 100 most influential people in the world in 2012 and 2017. In 2017 she received a star on the Hollywood Walk of Fame. In 2020, The New York Times ranked Davis ninth on its list of "The 25 Greatest Actors of the 21st Century".

Lindsey Olin Graham is an American politician serving as the senior United States Senator from South Carolina, a seat he has held since 2003. A member of the Republican Party, Graham served as chairman of the Senate Committee on the Judiciary from 2019 to 2021.

Stephon Stiles Gilmore is an American football cornerback for the New England Patriots of the National Football League (NFL). Gilmore played college football for South Carolina and was drafted by the Buffalo Bills tenth overall in the 2012 NFL Draft. After five seasons as a starting cornerback for the Bills and a Pro Bowl invite in 2016, Gilmore signed a 5-year, $65 million contract with New England in 2017. He has since emerged as one of the league's top defensive players, garnering three more Pro Bowl invites and first-team All-Pro recognitions in 2018 and 2019, as well as being named AP NFL Defensive Player of the Year in 2019.

Aziz Ismail Ansari is an American actor, writer, producer, director, and comedian. He is known for his role as Tom Haverford on the NBC series Parks and Recreation (2009–2015) and as creator and star of the Netflix series Master of None (2015–) for which he won several acting and writing awards, including two Emmys and a Golden Globe, which was the first award received by an Asian American actor for acting on television.

Temetrius Jamel "Ja" Morant is an American professional basketball player for the Memphis Grizzlies of the National Basketball Association (NBA). He played college basketball for the Murray State Racers, where he was a consensus first-team All-American as a sophomore in 2019. He was selected by the Grizzlies with the second overall pick in the 2019 NBA draft and named the NBA Rookie of the Year in 2020.

Vanna Marie White is an American television personality and film actress known as the hostess of Wheel of Fortune since 1982.

Dylann Storm Roof is an American white supremacist, neo-Nazi and mass murderer convicted for perpetrating the Charleston church shooting on June 17, 2015, in the U.S. state of South Carolina. During a Bible study at Emanuel African Methodist Episcopal Church, Roof killed nine people, all African Americans, including senior pastor and state senator Clementa C. Pinckney, and injured one other person. After several people identified Roof as the main suspect, he became the center of a manhunt that ended the morning after the shooting with his arrest in Shelby, North Carolina. He later confessed that he committed the shooting in hopes of igniting a race war. Roof's actions in Charleston have been widely described as domestic terrorism.

Brett Mason Rudolph III is an American football quarterback for the Pittsburgh Steelers of the National Football League (NFL). He played college football at Oklahoma State, where he was a three-year starter and won the Johnny Unitas Golden Arm Award during his last year. He was selected by the Steelers in the third round of the 2018 NFL Draft.

Dewey LaMarr Hoyt Jr. was an American professional baseball right-handed pitcher. He played in Major League Baseball for the Chicago White Sox and San Diego Padres from 1979 to 1986. He won the 1983 American League Cy Young Award and was an All-Star in 1985.

Cordarrelle Patterson, nicknamed "Flash", is an American football wide receiver and return specialist for the Chicago Bears of the National Football League (NFL). He was drafted by the Minnesota Vikings in the first round of the 2013 NFL Draft. He played college football at Tennessee.

Jay Wayne Jenkins, known professionally as Jeezy, is an American rapper, singer, songwriter, and actor. Signed to Def Jam Recordings since 2004, his major label debut Let's Get It: Thug Motivation 101 was released the following year and debuted at #2 on the Billboard 200, selling 172,000 copies in its first week and was later certified platinum by the Recording Industry Association of America (RIAA). Jeezy is credited, along with fellow Atlanta-based rappers T.I. and Gucci Mane, for helping to pioneer and popularize trap music with a mainstream audience.

Adriel Jeremiah Green is an American football wide receiver for the Cincinnati Bengals of the National Football League (NFL). He played college football at the University of Georgia for the Georgia Bulldogs, and was drafted by the Bengals fourth overall in the 2011 NFL Draft.