List of Famous people born in Missouri, United States of America

Clinton E. Frank was an American football player and advertising executive. He played halfback for Yale University, where he won both the Heisman Trophy and Maxwell Award in 1937. In 1954, he founded the Clinton E. Frank, Inc. advertising agency.

Alfred Hoblitzelle Clifford was an American mathematician born in St. Louis, Missouri who is known for Clifford theory and for his work on semigroups. He did his undergraduate studies at Yale and his PhD at Caltech, and worked at MIT, Johns Hopkins, and later Tulane University. The Alfred H. Clifford Mathematics Research Library at Tulane University is named after him.

Virgil Thomson was an American composer and critic. He was instrumental in the development of the "American Sound" in classical music. He has been described as a modernist, a neoromantic, a neoclassicist, and a composer of "an Olympian blend of humanity and detachment" whose "expressive voice was always carefully muted" until his late opera Lord Byron which, in contrast to all his previous work, exhibited an emotional content that rises to "moments of real passion".

Francis Thomas Sullivan, known professionally as Frank Sully, was an American film actor. He appeared in over 240 films between 1934 and 1968.

Janet Lynn Kavandi, a native of Carthage, Missouri, is an American scientist and a NASA astronaut. She is a veteran of three Space Shuttle missions, served as NASA's Deputy Chief of the Astronaut Office, and was the Center Director at the NASA Glenn Research Center in Cleveland, Ohio from March 2016 until her retirement from NASA in September 2019. Kavandi is Senior Vice President of Sierra Nevada Corporation's Space Systems business area.

Ellis Short is a London-based American businessman and founder of Kildare Partners, a private equity fund investing in distressed European real estate assets. Short was also the owner and chairman of English football club Sunderland A.F.C. from September 2008 to April 2018.

Paul Smith is an American comic book artist, known for his work on The Uncanny X-Men, X-Factor, American Flagg!, Nexus, GrimJack and his creator-owned book, Leave It to Chance.

Robert Walter Kustra is an American politician and academic administrator who served as the Lieutenant Governor of Illinois from 1991 to 1998 and the President of Boise State University from 2003 to 2018.