List of Famous people born in Kyōto Prefecture, Japan

Tasuku Honjo is a Japanese physician-scientist and immunologist. He shared the 2018 Nobel Prize in Physiology or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1). He is also known for his molecular identification of cytokines: IL-4 and IL-5, as well as the discovery of activation-induced cytidine deaminase (AID) that is essential for class switch recombination and somatic hypermutation.

Goshi Hosono is a Japanese politician and a member of the House of Representatives in the Diet. A native of Ōmihachiman, Shiga and graduate of Kyoto University, he was elected to the House of Representatives for the first time in 2000. He was the Minister of Environment and Minister of State for Nuclear Power Policy and Administration in the cabinet of Yoshihiko Noda. He represents the 5th District of Shizuoka prefecture.

Shinsuke Nakamura is a Japanese professional wrestler and former mixed martial artist. He is currently signed to WWE, where he performs on the SmackDown brand.

Sadakazu Tanigaki is a Japanese politician who served as a member of the House of Representatives from 1998 to 2016, as Minister of Finance from 2003 to 2006, as President of the Liberal Democratic Party and Leader of the Opposition from 2009 to 2012, as Minister of Justice from 2012 to 2014, and as LDP Secretary-General from 2014 to 2016. He was only the second LDP leader who was not simultaneously Prime Minister of Japan. He retired from politics following a spinal cord injury in 2016 that left him confined to a wheelchair.

Shigeru Miyamoto is a Japanese video game designer, producer and game director at Nintendo, where he serves as one of its representative directors. He is the creator of some of the most acclaimed and best-selling game franchises of all time, including Mario and The Legend of Zelda.

Asami Mizukawa is a Japanese actress. She grew up in Ibaraki, Osaka.

Kuranosuke Sasaki is a Japanese actor, known primary for his roles in Japanese television drama.

Masakazu Tamura is a Japanese film and theatre actor.

Seiji Maehara is a Japanese politician and was the leader of the Democratic Party from 1 September 2017 until its dissolution later that month. He has also been a member of the House of Representatives of Japan since 1993.

Shizuka Nakamura is a Japanese gravure idol and actress who is represented by the talent agency Oscar Promotion. She was a member of Pretty Club 31 and Teenage Club.