List of Famous people born in Pennsylvania, United States of America

Frances Hamilton Arnold is an American chemical engineer and Nobel Laureate. She is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology (Caltech). In 2018, she was awarded the Nobel Prize in Chemistry for pioneering the use of directed evolution to engineer enzymes. Frances Arnold is a director of Alphabet Inc. since December 2019.

Morton David Alpern, better known as Marty Allen, was an American comedian, actor, and philanthropist. He worked as a comedy headliner in nightclubs, as a dramatic actor in television roles, and was once called "The Darling of Daytime TV". He also appeared in films, notably the 1966 spy comedy The Last of the Secret Agents? During his comedy career, Allen also toured military hospitals, performed for veterans, and for active military personnel.

Jazmine Marie Sullivan is an American singer-songwriter. Born and raised in Philadelphia, Pennsylvania, her debut album, Fearless, was released in 2008 to commercial and critical success. The record topped Billboard's Top R&B/Hip-Hop Albums chart and was certified gold by the Recording Industry Association of America (RIAA). It spawned four singles, including "Need U Bad" and "Bust Your Windows", both of which peaked in the top 40 of the Billboard Hot 100 chart and the former of which became Sullivan's first and only number one on the Billboard Hot R&B/Hip-Hop Songs chart.

Elaine Iva May is an American comedian, film director, screenwriter, playwright, and actress. She made her initial impact in the 1950s with her improvisational comedy routines with Mike Nichols, performing as Nichols and May.

Elizabeth Ann Behrs is an American actress and writer known for her starring role as Caroline Channing in the CBS comedy series 2 Broke Girls. The show ran for six seasons and earned Behrs praise and nominations for the Teen and the People's Choice Awards. Having made her screen debut in the 2009 comedy film American Pie Presents: The Book of Love, she later ventured into television roles. After 2 Broke Girls, Behrs returned to feature films with the 2015 productions Chasing Eagle Rock and Hello, My Name Is Doris. She voiced Carrie Williams in the animated film Monsters University (2013) and Moochie in the television series Home: Adventures with Tip & Oh, and was cast as Gemma Johnson in the CBS sitcom The Neighborhood.

Marcus Paul Blucas is an American actor whose roles include Riley Finn in Buffy the Vampire Slayer, Matthew Donnelly in Necessary Roughness and abolitionist John Hawkes in Underground. Prior to his acting career, he played college basketball with the Wake Forest Demon Deacons.

Steven Ormain Cunningham is an American professional boxer who held the IBF cruiserweight title twice between 2007 and 2011. His nickname, "USS", is a reference to his US Navy service on the aircraft carriers USS America and USS Enterprise between 1994 and 1998.

Randy Douglas Edsall is an American football coach who is currently in his second stint as the head football coach at the University of Connecticut. He was director of football research-special projects for the Detroit Lions of the National Football League (NFL) previously in 2016. He was the head coach at the University of Maryland from 2011 to 2015. Edsall was previously the head coach at Uconn from 1999 until the 2011 Fiesta Bowl, and oversaw the program's promotion from the NCAA Division I-AA level to Division I-A. He is UConn's all-time leader in wins and games coached.

Lizabeth Virginia Scott was an American actress, known for her "smoky voice" and being "the most beautiful face of film noir during the 1940s and 1950s". After understudying the role of Sabina in the original Broadway and Boston stage productions of The Skin of Our Teeth, she emerged in such films as The Strange Love of Martha Ivers (1946), Dead Reckoning (1947), Desert Fury (1947), and Too Late for Tears (1949). Of her 22 films, she was the leading lady in all but one. In addition to stage and radio, she appeared on television from the late 1940s to early 1970s.

Keith Allen Haring was an American artist whose pop art and graffiti-like work grew out of the New York City street culture of the 1980s. Much of his work includes sexual allusions that turned into social activism. He achieved this by using sexual images to advocate for safe sex and AIDS awareness.