List of Famous people born in Pennsylvania, United States of America

James Philip Bagian, MD, PE, is an American physician, engineer, and former NASA astronaut of Armenian descent. During his career as an astronaut, he logged 337 hours of space-flight, over two missions, STS-29 and STS-40. After leaving NASA in 1995, Bagian was elected as a member of the Institute of Medicine. He was also elected as member into the National Academy of Engineering in 2000 for the integration of engineering and medical knowledge in applications to aerospace systems, environmental technology, and patient safety.

Edward William May Jr. was an American composer, arranger and trumpeter. He composed film and television music for The Green Hornet (1966), The Mod Squad (1968), Batman, and Naked City (1960). He collaborated on films such as Pennies from Heaven (1981), and orchestrated Cocoon, and Cocoon: The Return, among others.

Katharine Elizabeth Garde was an American stage, radio, film and television actress.

Monica Patrice Calhoun is an American film and television actress. Calhoun is best known for her roles in the films Bagdad Cafe, The Players Club, The Salon, The Best Man, and its sequel The Best Man Holiday. Calhoun was nominated for an Emmy Award for her performance in the CBS Schoolbreak Special "Different Worlds: A Story of Interracial Love" (1993). Calhoun was nominated for an NAACP Image Award for Outstanding Actress in a Motion Picture for her portrayal of Mia Morgan in the 1999 comedy–drama film The Best Man.

Robert Lutz is a former amateur and professional tennis player of the 1960s and 1970s. He and his longtime partner Stan Smith were one of the best doubles teams of all time. Bud Collins ranked Lutz as world No. 7 in singles in 1972. Between 1967 and 1977, he was ranked among the top-10 American players eight times, with his highest ranking being No. 5 in both 1968 and 1970.

Oscar Fraley was an American sports writer and author, perhaps best known, with Eliot Ness, as the co-author of the American memoir The Untouchables.

David Wellington is an American writer of horror fiction, best known for his Zombie trilogy. He also writes science fiction as D. Nolan Clark.

William Moore was a Pennsylvania statesman and politician of the Revolutionary era. He served as Vice-President of Pennsylvania from 1779 to 1781, and then as President from 1781 to 1782.. Moore was the only man formally elected to both offices. He was also a judge, state legislator, director of the Bank of Pennsylvania and trustee of the University of Pennsylvania.

Robert Karl Kurz is an American former professional basketball player. He played one season in the National Basketball Association (NBA) for the Golden State Warriors, and later played in the top leagues in Spain, Germany, and France.

Leonard Solomon Lerman was an American scientist most noted for his work on DNA.