List of Famous people born in Palermo, Italy

Mario Balotelli Barwuah is an Italian professional footballer who plays as a striker for Serie B club Monza.

Marco Cecchinato is an Italian professional tennis player. On 29 April 2018, he won his first ATP World Tour title at the 2018 Hungarian Open. He became the first Sicilian tennis player to win an ATP title. His best Grand Slam result is a semifinal at the 2018 French Open. However, in the other three Majors he has not won a match.

Giovanni "John" Gambino was an Italian-born American mobster. Born in Palermo, Sicily, he became a made member of the Gambino crime family in 1975 and a capodecina or captain, and head of the crime family's Sicilian faction, appointed by family boss John Gotti in 1986, according to Mafia turncoat Sammy Gravano.

Sergio Mattarella is an Italian politician, jurist, academic and lawyer, who is serving as the 12th and current President of the Italian Republic, since February 2015.

Mary Ann Vecchio is one of two subjects in the Pulitzer Prize-winning photograph by photojournalism student John Filo during the immediate aftermath of the Kent State shootings on May 4, 1970.

Domenico "Italian Dom" Cefalù, also known as "Greaseball", "Dom and Cheese" and "Dom from 18th Avenue", is currently the reputed boss of the Gambino crime family and influential leader of the organization's Sicilian faction.

Luca Guadagnino is an Italian filmmaker. He has collaborated a number of times with actress Tilda Swinton, including on the films The Protagonists (1999), I Am Love (2009), A Bigger Splash (2015) and Suspiria (2018), a remake of the 1977 film of the same name.

Rosalia Lombardo was an Italian child who died of pneumonia, resulting from the Spanish flu, one week shy of her second birthday. Rosalia's father, Mario Lombardo, was grieving her death, asked Alfredo Salafia, an embalmer, to preserve her remains. Her mummified body, sometimes called "Sleeping Beauty", was one of the last corpses to be admitted to the Capuchin catacombs of Palermo in Sicily.

Giovanni Falcone was an Italian judge and prosecuting magistrate. From his office in the Palace of Justice in Palermo, Sicily, he spent most of his professional life trying to overthrow the power of the Sicilian Mafia. After a long and distinguished career, culminating in the Maxi Trial in 1986–1987, on 23 May 1992, Falcone was assassinated by the Corleonesi Mafia in the Capaci bombing, on the A29 motorway near the town of Capaci.

Sebastiano Tusa was an Italian archaeologist and politician who served as councilor for Cultural Heritage for the Sicilian Region of Italy from 11 April 2018 until his death on 10 March 2019. Tusa also served as a professor of paleontology at the Suor Orsola Benincasa University of Naples.