List of Famous people born in Duval County, United States of America

Michael McCorkle "Mac" Jones is an American football quarterback who most recently played for the Alabama Crimson Tide.

Ronald Dion DeSantis is an American attorney and politician serving as the 46th and current governor of Florida since 2019. A member of the Republican Party, he previously represented Florida's 6th congressional district in the United States House of Representatives from 2013 to 2018. After graduating from Yale University and Harvard Law School, DeSantis served as an officer and attorney in the Judge Advocate General's Corps, U.S. Navy (JAG).

Ronald "RJ" Cyler II is an American actor. He is best known for his roles in Me and Earl and the Dying Girl, Power Rangers, I'm Dying Up Here and Scream.

Steven R. Donziger is an American attorney known for his legal battles with Chevron, particularly the Lago Agrio oil field case.

Grayson James Allen is an American professional basketball player for the Memphis Grizzlies of the National Basketball Association (NBA). He played four years of college basketball at Duke University.

Joshua Treadwell McCown is an American football quarterback for the Houston Texans of the National Football League (NFL). He attended Jacksonville High School in Jacksonville, Texas, where he was named the East Texas Player of the Year and earned All-State honorable mention honors as a senior. McCown then played three seasons of college football for the Mustangs of Southern Methodist University, where he passed for totals of 4,022 yards, 27 touchdowns, and 34 interceptions. He then transferred to play his final season of college football for the Bearkats of Sam Houston State University. In his only season with the Bearkats, he threw for 3,481 yards, 32 touchdowns and 12 interceptions, earning Southland Football League Player of the Year and Third-team Division I-AA All-American honors.

Valdez Venita Demings is an American politician and former police officer serving as the U.S. Representative for Florida's 10th congressional district since 2017. The district covers most of the western half of Orlando and includes much of the area around Orlando's resort parks. It also includes many of Orlando's western suburbs, such as Apopka and Winter Garden. From 2007 to 2011, she was Chief of the Orlando Police Department, the first woman to lead the department, capping a 27-year career with the department.

Frank Manning was an American dancer, instructor, and choreographer. Manning is considered one of the founders of Lindy Hop, an energetic form of the jazz dance style known as swing.

Nehemiah Lamar Harden, professionally known as SpotemGottem, is an American rapper and songwriter. He is best known for his 2020 hit single "Beat Box", which peaked at number 12 on the Billboard Hot 100. He is signed to Geffen Records, Interscope Records and Rebel Music.

Ottis Elwood Toole was an American drifter and serial killer who was convicted of six counts of murder. Like his companion Henry Lee Lucas, Toole made confessions he then later recanted, which resulted in murder convictions. The discrediting of the case against Lucas for crimes for which Toole had offered corroborating statements created doubts as to whether either was a genuine serial killer or, as Hugh Aynesworth suggested, both were merely compliant interviewees whom police used to clear unsolved murders from the books.