List of Famous people born in Delaware, United States of America

Daniel Nathans was an American microbiologist. He shared the 1978 Nobel Prize in Physiology or Medicine for the discovery of restriction enzymes and their application in restriction mapping.

Michael Newbold Castle is an American attorney and politician who was governor of Delaware (1985–92) and the U.S. Representative for Delaware's at-large congressional district (1993–2011). He is a member of the Republican Party.

Caleb Rodney was an American merchant and politician from Lewes, in Sussex County, Delaware. He was a member of the Federalist Party, who served in the Delaware General Assembly and as Governor of Delaware.

Betty Jean Ward, professionally known as B. J. Ward, is an American actress. She is the creator and star of Stand-Up Opera, a musical one-woman show, and is a licensed aviator.

Marjorie "Midge" Rendell is an American attorney and jurist serving as a Senior United States Circuit Judge of the United States Court of Appeals for the Third Circuit and a former First Lady of Pennsylvania. In 2003, she was named to the PoliticsPA list of "Pennsylvania's Most Politically Powerful Women".

David Penrose Buckson was an American lawyer and politician from Camden in Kent County, Delaware. He was a veteran of World War II and a member of the Republican Party, who served as the 15th Lieutenant Governor of Delaware, for nineteen days the 63rd Governor of Delaware and the 37th Attorney General of Delaware.

Dennis P. Williams is an American politician who served as the Mayor of Wilmington, Delaware from 2013 to 2017. He previously served in the Delaware House of Representatives from 1995 to 2013 in a district based in northern Wilmington. He won the mayoral election for the city of Wilmington on November 6, 2012. Williams ran for a second term as mayor in 2016, but lost in the primary to Mike Purzycki, who succeeded him as mayor.

Jack Alan Markell is an American former businessman and politician who served as the 73rd governor of Delaware from 2009 to 2017. He is a member of the Democratic Party.

William Alland was an American actor, film producer and writer, mainly of Western and science-fiction/monster films, including This Island Earth, It Came From Outer Space, Tarantula!, The Deadly Mantis, The Mole People, The Colossus of New York, The Space Children, and the three Creature from the Black Lagoon films. He worked frequently with director Jack Arnold. Alland is also remembered for his acting role as reporter Thompson, who investigates the meaning of "Rosebud" in Orson Welles's Citizen Kane (1941).

Matthew P. Denn is an American lawyer and politician from New Castle County, Delaware. He served as the 45th Attorney General of Delaware from 2015 until 2019. Denn previously served as the 25th Lieutenant Governor of Delaware from 2009 to 2015, and was the Insurance Commissioner of Delaware from 2005 to 2009.