List of Famous people born in Colón Province, Panama

John Sidney McCain III was an American statesman and United States Navy officer who served as a United States Senator for Arizona from 1987 until his death in 2018. He previously served two terms in the United States House of Representatives and was the Republican nominee for president of the United States in the 2008 election, which he lost to Barack Obama.

Victoria Ann Toensing is an American attorney, Republican Party operative and with her husband, Joseph diGenova, a partner in the Washington law firm diGenova & Toensing. Toensing and diGenova frequently appeared on Fox News and Fox Business channels, until diGenova used a November 2019 appearance to spread conspiracy theories about George Soros, leading to widespread calls for him to be banned from the network. In 2019, Toensing and diGenova were embroiled in the Trump–Ukraine scandal. The couple have worked with Rudy Giuliani in support of President Donald Trump beginning in 2018, and were named to join a legal team led by Giuliani to overturn the results of the 2020 United States presidential election in which Trump was defeated.

Benjamin Ambrosio Oglivie Palmer is a Panamanian former professional baseball left fielder, who played in Major League Baseball (MLB) for the Boston Red Sox (1971–1973), Detroit Tigers (1974–1977), and Milwaukee Brewers (1978–1986). He also played two seasons in Nippon Professional Baseball (NPB) for the Kintetsu Buffaloes (1987–1988). Oglivie batted and threw left-handed.

Juan Antonio Williams is a Panamanian-American journalist and political analyst for Fox News Channel. He writes for several newspapers, including The Washington Post, The New York Times, and The Wall Street Journal, and has been published in magazines such as The Atlantic Monthly and Time. Williams has worked as an editorial writer, an op-ed columnist, a White House correspondent, and a national correspondent. He is a registered Democrat.

Reinaldo Antonio Stennett Porte was a Panamanian professional baseball second baseman, who played in Major League Baseball (MLB) for the Pittsburgh Pirates (1971–79) and San Francisco Giants (1980–81). He batted and threw right-handed. A World Series champion with the Pirates in 1979, Stennett is one of three players to collect seven hits in a game, which he did in a 22–0 victory over the Chicago Cubs, in 1975. Stennett was also a member of the first all-black starting lineup in big league history.

Alfonso Teofilo Brown, better known as Panama Al Brown, was a Panamanian professional boxer. He made history by becoming boxing's first Latin American world champion, and is widely regarded as one of the greatest bantamweight boxers in history.

Armando Enrique Cooper Whitaker is a Panamanian professional footballer who plays as a midfielder for Maccabi Petah Tikva and Panama national football team.

Julio César Dely Valdés is a Panamanian former professional footballer who played as a striker. He is a twin brother of Jorge Dely Valdés and younger brother of Armando Dely Valdés.

Guillermo Jones is a Panamanian professional boxer. He held the WBA cruiserweight title from 2008 to 2012, and challenged twice for the WBA super welterweight title in 1998.

Édgar Yoel Bárcenas Herrera is a Panamanian professional footballer who plays as a winger for Liga MX club Mazatlán and the Panama national team.