List of Famous people named Isaac

Isaac Hamilton Rapp, was a notable American architect who has been called the "Creator of the Santa Fe style." He was born in Orange, New Jersey.

Isaac ben Jacob Alfasi ha-Cohen (1013–1103) - also known as the Alfasi or by his Hebrew acronym Rif, was an Algerian Talmudist and posek. He is best known for his work of halakha, the legal code Sefer Ha-halachot, considered the first fundamental work in halakhic literature. His name "Alfasi" means "of Fez" in Arabic, but opinions differ as to whether he ever lived in Fez.

Isaac ben Sheshet Perfet (1326–1408) was a Spanish Talmudic authority, also known by his acronym, Rivash. He was born at Valencia and settled early in life at Barcelona, where he studied at the school of Nissim of Gerona.

Isaac Leopold Rice was a German-born Jewish American businessman, investor, musicologist, author, and chess patron. As part of a successful career in the manufacturing industry, in 1899 he acquired the Holland Torpedo Boat Company, which was renamed the Electric Boat Company and produced submarines for the U.S. and British navies. It continues today as General Dynamics Electric Boat.

Isaac "Ike" Perlmutter is an Israeli-American businessperson and financier. He is the chairman and CEO Emeritus of Marvel Entertainment. He was also the owner of Remington Products and Marvel Toys.