List of Famous people born in South Holland, Kingdom of the Netherlands

Willem Johan "Pim" Kolff was a pioneer of hemodialysis, artificial heart, as well as in the entire field of artificial organs. Willem is a member of the Kolff family, an old Dutch patrician family. He made his major discoveries in the field of dialysis for kidney failure during the Second World War. He emigrated in 1950 to the United States, where he obtained US citizenship in 1955, and received a number of awards and widespread recognition for his work.

Onno Hoes is a Dutch politician of the People's Party for Freedom and Democracy (VVD) and businessman. He was the acting Mayor of Haarlemmermeer from 28 November 2017 till 10 July 2019

Willemine Elisabeth Edzardine (Lita) de Ranitz was a Dutch art collector. Her collection of dollhouses and related items is now in the Historical Museum of the Hague.

Johannes Jisse (Hans) Duistermaat was a Dutch mathematician. He studied mathematics at Utrecht University from 1959 to 1965 and obtained his PhD degree there in 1968 under the supervision of Hans Freudenthal. After a postdoctoral year 1969–70 in Lund, where he learned Fourier integral operators from Lars Hörmander, he went in 1971–74 to Nijmegen, where he became full professor in 1972. In 1974 he returned to Utrecht on the chair of professor Freudenthal, where he stayed until his unexpected death in March 2010.

Jacob de Witt, heer van Manezee, Melissant and Comstryen was a burgomaster of Dordrecht and the son of a timber merchant. He was also a younger brother of Andries de Witt and the father of Johan and Cornelis de Witt.

Willem Jacobsz. Delff was a Dutch Golden Age engraver and painter.

Sir Edward Baldwin Malet, 4th Baronet was a British diplomat.

Johannes Diderik van der Waals was a Dutch theoretical physicist and thermodynamicist famous for his pioneering work on the equation of state for gases and liquids. Van der Waals started his career as a school teacher. He became the first physics professor of the University of Amsterdam when in 1877 the old Athenaeum was upgraded to Municipal University. Van der Waals won the 1910 Nobel Prize in physics for his work on the equation of state for gases and liquids.

Willem de Kooning was a Dutch-American abstract expressionist artist. He was born in Rotterdam and moved to the United States in 1926, becoming an American citizen in 1962. In 1943, he married painter Elaine Fried.