List of Famous people born in South Carolina, United States of America

Lucas Hendley Glover is an American professional golfer who currently plays on the PGA Tour. He is best known for winning the 2009 U.S. Open.

Johnny Reid "John" Edwards is an American lawyer and former politician who served as a U.S. senator from North Carolina. He was the Democratic nominee for Vice President in 2004, and was a candidate for the Democratic presidential nomination in 2004 and 2008.

William Anthony Perry is a former American football defensive lineman who played in the National Football League (NFL) for ten seasons, primarily with the Chicago Bears. Nicknamed "The Refrigerator" for his imposing size, he played college football at Clemson University and was selected by the Bears in the first round of the 1985 NFL Draft. Perry gained popularity during his rookie season as a member of the Bears team that won the franchise's first Super Bowl in Super Bowl XX. During the season, Perry occasionally played fullback in goal line situations and set the then-record for the heaviest player to score a touchdown at 335 lb (152 kg). He remains the heaviest player to score a touchdown in the Super Bowl and has the largest Super Bowl ring at size 25.

Morris Jackson "Mo" Brooks Jr. is an American attorney and politician who has served as the United States Representative for Alabama's 5th congressional district since 2011. The district is based in Huntsville and stretches across the northern third of the state. In 2017, he finished third in the Republican primary for the U.S. Senate seat vacated by Jeff Sessions upon Sessions's confirmation as U.S. Attorney General.

Mary Laurence "Lauren" Hutton is an American model and actress. Born and raised in the southern United States, Hutton relocated to New York City in her early adulthood to begin a modeling career. Though she was initially dismissed by agents for a signature gap in her teeth, Hutton signed a modeling contract with Revlon in 1973, which at the time was the biggest contract in the history of the modeling industry.

Thomas Jonathan Jackson Ravenel is an American politician and reality television star. He is the son of former South Carolina Congressman Arthur Ravenel Jr.

Jaime R. Harrison is an American politician, who is the current chairman of the Democratic National Committee, after previously serving as the chair of the South Carolina Democratic Party from 2013 to 2017. Harrison ran against incumbent senator Lindsey Graham for the South Carolina U.S. Senate seat in the 2020 election. Graham defeated Harrison by ten percentage points, 54% to 44% during the November 3, 2020, general election. Harrison broke U.S. Senate campaign fundraising records by raising $109 million.

Edwin Cole McCain is an American singer-songwriter and guitarist. His songs "I'll Be" (1998) and "I Could Not Ask for More" (1999) were radio top-40 hits in the U.S., and five of his albums have reached the Billboard 200. In all, McCain has released eleven albums, with his first two being released independently.

Martavis Alexander Bryant is a gridiron football wide receiver for the Toronto Argonauts of the Canadian Football League (CFL). He played college football at Clemson, and was drafted by the Pittsburgh Steelers in the fourth round of the 2014 NFL Draft.

Raven Saunders is an American track and field athlete who competes in the shot put and discus throw. She was the silver medalist in the 2020 Tokyo Olympics, throwing a distance of 19.79 m. She won three NCAA collegiate titles in the shot put for the University of Mississippi. She was a world junior medalist in 2014 and the Pan American junior champion in 2015. She holds a personal record of 19.96 m for the shot put.