List of Famous people born in South Carolina, United States of America

Jasmine Camacho-Quinn is a Puerto Rican track and field athlete, who specializes in the 100 m hurdles. She participated at the 2016 Summer Olympics in the 100 metres hurdles event. Her personal best of 12.32, set in 2021 is tied for the #7 time in history.

Teyonah Parris is an American actress. She began her career playing a recurring role as Dawn Chambers in the AMC drama series, Mad Men (2012–2015), before landing her breakthrough role in the 2014 independent film Dear White People. In 2015, Parris starred in the satirical drama film Chi-Raq directed by Spike Lee.

Lenard Larry McKelvey, known professionally as Charlamagne tha God, is an American radio presenter, television personality, and author. He is a co-host of the nationally syndicated radio show The Breakfast Club with DJ Envy and Angela Yee, all of whom were inducted in the Radio Hall of Fame in 2020 for their work on the show.

Thomas Ellis Gibson is an American actor and director. He portrayed Daniel Nyland in the CBS television series Chicago Hope (1994–2000), Greg Montgomery in the ABC television series Dharma & Greg (1997–2002) and Aaron Hotchner in the CBS television series Criminal Minds (2005–2016).

Alshon Jemell Jeffery is an American football wide receiver for the Philadelphia Eagles of the National Football League (NFL). He played college football at South Carolina, and was drafted by the Chicago Bears in the second round of the 2012 NFL Draft. As a member of the Eagles, he won Super Bowl LII over the New England Patriots.

David Patten was an American football wide receiver. He was signed by the Albany Firebirds as a street free agent in 1996. Starting in 1997, he played in the National Football League (NFL) and competed for 12 seasons through 2008. He played college football at Western Carolina.

Shelton J. Benjamin is an American professional wrestler currently signed to WWE, performing on the Raw brand. He is a part of The Hurt Business alongside MVP, Bobby Lashley and Cedric Alexander and is one half of the current WWE Raw Tag Team Champions with Cedric Alexander in their first reign as a team and Benjamin's third reign overall.

Carl Fleming Edwards Jr. is an American professional baseball pitcher for the Atlanta Braves organization. He previously played in Major League Baseball (MLB) for the Chicago Cubs, San Diego Padres, and Seattle Mariners.

Robert Quinn is an American football outside linebacker for the Chicago Bears of the National Football League (NFL). He played college football at North Carolina, and was drafted by the St. Louis Rams with the 14th pick in the first round of the 2011 NFL Draft.

Gaylord Jackson Perry is an American former professional baseball player. He played in Major League Baseball as a right-handed pitcher for eight different teams from 1962 to 1983. During a 22-year baseball career, Perry compiled 314 wins, 3,534 strikeouts, and a 3.11 earned run average. He was elected to the Baseball Hall of Fame in his third year of eligibility in 1991.