List of Famous people born in Santa Fe Province

Juan José Imhoff is an Argentine rugby union footballer. He plays as a wing and fullback.

Roberto Néstor Sensini is an Argentine football manager and former player, who played as a centre-back or defensive midfielder. As a player with the Argentina national team, he won both the 1991 and 1993 Copa América, also finishing in third place in the 1989 edition of the tournament. He also represented his nation in the 1990, 1994, and 1998 FIFA World Cup finals, finishing in second place at the 1990 World Cup. Furthermore, he won an Olympic silver medal with Argentina at the 1996 Olympics.

Esteban Andrés Solari Poggio is an Argentine former professional footballer who played as a striker.

Pablo Alejandro Marini is an Argentine former football player and current manager of Uruguayan Primera División club Montevideo City Torque.

Antonio Bonfatti is an Argentine physician and politician from the Socialist Party, who was Governor of Santa Fe. Since April 2016, he has been the leader of the Socialist Party.

Clara Mónica Gutiérrez, is an Argentine journalist.

Tomás Alberto Costa is an Argentine footballer who plays as a central midfielder.

Vanina Noemí Correa is an Argentine footballer who plays as a goalkeeper for Spanish Primera División club RCD Espanyol and the Argentina women's national team.

Jorge Remigio Pautasso is a former football player and assistant coach of the Argentina national football team who taught Gerardo Martino.

Emanuel Biancucchi Cuccittini is an Argentine footballer who plays as a midfielder for Campeonato Brasileiro club Vila Nova.