List of Famous people born in Santa Fe Province, Argentina

Lucio Fontana was an Argentine-Italian painter, sculptor and theorist. He is mostly known as the founder of Spatialism.

Rinaldo Fidel Brédice was an Argentine Roman Catholic bishop.

Mariano Andrés Soso is an Argentine football manager.

Pedro Elías Zadunaisky was an Argentine astronomer and mathematician who plotted the orbit of Saturn's most-distant moon, Phoebe, as well as several comets including Halley's Comet, and various satellites including Explorer I.

Moisés Julio Blanchoud was an Argentine Prelate of the Roman Catholic Church.

Agustín Magaldi was a tango and milonga singer. His nickname was "the sentimental voice of Buenos Aires." Magaldi took part in the opening broadcasts of Argentina's LOY Radio Nacional in July 1924.

Pablo Andrés Sánchez Spucches, nicknamed Vitamina, is an Argentine retired footballer who played as a midfielder, and is a current manager.

Rafael Antonio Bielsa Caldera is an Argentine Justicialist Party politician from Rosario, province of Santa Fe. Since 2020 he has been Argentina's ambassador to Chile.

César Fabián Delgado Godoy is an Argentine former professional footballer who played as a winger. He also played as a central midfielder, making piercing forward runs through the center of the opposition's defence. His nickname "Chelito" is derived from that of Marcelo Delgado because of their same last name. Since 2013, he also holds Mexican citizenship.