List of Famous people born in Port Elizabeth, South Africa

Siyamthanda Kolisi is a South African professional rugby union player who currently captains the South Africa national team and also plays club rugby for the Stormers in Super Rugby and Western Province in the Currie Cup. He generally plays as a flanker. In 2018, Kolisi was appointed captain of the Springboks, becoming the first black man to hold the position, and eventually leading the South African Rugby team to victory in the 2019 Rugby World Cup Final against England. In December 2019, Kolisi was named in New African magazine's list of 100 Most Influential Africans.

Johan 'Rassie' Erasmus is a South African rugby union coach and former player. He has been the head coach of the South African national team since 2018, doubling up on his duties as the first ever SARU Director of Rugby, which he was appointed towards the end of 2017. He led South Africa to win the 2019 Rugby World Cup, and he subsequently won the 2019 World Rugby Coach of the Year award.

Patrick Soon-Shiong is a South African-American transplant surgeon, billionaire businessman, bioscientist, and media proprietor. He is the inventor of the drug Abraxane, which became known for its efficacy against lung, breast, and pancreatic cancer. Soon-Shiong is the founder of NantWorks, a network of healthcare, biotech, and artificial intelligence startups; an adjunct professor of surgery and executive director of the Wireless Health Institute at the University of California, Los Angeles; and a visiting professor at Imperial College London and Dartmouth College. Soon-Shiong has published more than 100 scientific papers and has more than 230 issued patents worldwide on advancements spanning numerous fields in technology and medicine.

Rodney (Morgan) Howard-Browne is a South African-born American Christian evangelist and conspiracy theorist. He has resided in Tampa, Florida since the mid-1990s and is pastor of The River Church in Tampa Bay. The River is considered both Pentecostal and Charismatic with revival meetings, led by Howard-Browne, known for those in the audience breaking into "holy laughter". Howard-Browne is the head of Revival Ministries International, a group he and his wife founded in 1997.

Adrienne "Adie" Camp is a South African singer and songwriter, who is known as the lead singer of the Christian pop-rock band the Benjamin Gate before the group disbanded in 2003. She briefly contributed to other artist's albums, namely her duet with rapper John Reuben featured on his album Professional Rapper and her background vocals on husband Jeremy Camp's albums Restored and Live Unplugged, after the Benjamin Gate disbanded.

Colin Alexander Ingram is a South African cricketer who currently plays for Glamorgan and Peshawar Zalmi. He represented South Africa in One Day (ODI) and Twenty20 Internationals (T20I) between 2010 and 2013, scoring a century on his ODI debut against Zimbabwe.

Schalk Willem Petrus Burger Jr. is a South African professional rugby union player. He plays as a flanker for Saracens in the English Premiership and has won 86 caps for South Africa.

Dorothy Bernard was an American actress of the silent era. She appeared in 87 films between 1908 and 1956.

Michael John Catt OBE is a South African-born former rugby union player who played for the England national rugby union team. He played professionally for the clubs London Irish and Bath. He earned 75 international caps for England and played in two World Cup Finals, in 2003 and 2007. With his appearance in the October 2007 final, at age 36 years 1 month, he became the oldest ever player to play in a Rugby World Cup final. Since 2008, Catt has coached various rugby teams, and has since 2019 been an assistant coach for the Ireland national rugby team.

Daniel Alexander "Danny" Jordaan is the president of the South African Football Association (SAFA). He is a former lecturer, politician and anti-apartheid activist. He led South Africa's successful 2010 FIFA World Cup bid, the first successful one for Africa, as well as the country's unsuccessful bid four years earlier for the 2006 FIFA World Cup, and was the Chief Executive Officer of the 2010 FIFA World Cup South Africa. He is also the former Mayor of the Nelson Mandela Bay Metropolitan Municipality, having served from May 2015 until August 2016.