List of Famous people born in Pennsylvania, United States of America

Nathaniel Kahn is an American filmmaker. His documentaries My Architect (2003) – about his father, the architect Louis Kahn – and Two Hands (2006) were nominated for Academy Awards. His mother is Harriet Pattison.

Sidney L. Miller was an American actor, director and songwriter.

Whittaker Chambers was an American writer-editor, who, after early years as a Communist Party member (1925) and Soviet spy (1932–1938), defected from the Soviet underground (1938), worked for Time magazine (1939–1948), and then testified about the Ware group in what became the Hiss case for perjury (1949–1950), often referred to as the trial of the century, all described in his 1952 memoir Witness. Afterwards, he worked as a senior editor at National Review (1957–1959). US President Ronald Reagan awarded him the Presidential Medal of Freedom posthumously in 1984.

Nathaniel Lester Lanin was an American jazz and pop music bandleader. He was famous for long, smoothly arranged medleys, at a consistent rhythm and tempo, which were designed for continuous dancing. Lanin's career began in the late 1920s and his popularity increased through the advent of the LP era. Starting with Epic Records in the middle of the 1950s, he recorded a string of albums for several labels, many of which hit the US Billboard 200.

Alexander James Dallas was an officer in the United States Navy.

Nancy Messonnier is an American physician who serves as the director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention. She is working on the CDC response to the COVID-19 pandemic in the United States.

Stanley Frank Musial, nicknamed Stan the Man, was an American baseball outfielder and first baseman. He spent 22 seasons in Major League Baseball (MLB), playing for the St. Louis Cardinals, from 1941 to 1944 and from 1946 to 1963. Widely considered to be one of the greatest and most consistent hitters in baseball history, Musial was a first-ballot inductee into the Baseball Hall of Fame in 1969. He batted .331 over the course of his career and set National League (NL) records for career hits (3,630), runs batted in (1,951), games played (3,026), at bats (10,972), runs scored (1,949) and doubles (725). His 475 career home runs then ranked second in NL history behind Mel Ott's total of 511. A seven-time batting champion, he was named the National League's (NL) Most Valuable Player (MVP) three times and was a member of three World Series championship teams. He also shares the major league record for the most All-Star Games played (24) with Hank Aaron and Willie Mays.

Barbara Hackman Franklin is an American government official, corporate director, and business executive. She served as the 29th U.S. Secretary of Commerce from 1992–1993 to President George H.W. Bush, during which she led a Presidential mission to China.

Patricia Crowley is an American actress.