List of Famous people born in Lake Charles, United States of America

Zachary Levi Pugh is an American actor, comedian, and singer. He received critical acclaim for starring as Chuck Bartowski in the series Chuck, and as the title character in Shazam!, as a part of the DC Extended Universe.

Matthew Garrett Forte is a former American football running back who played ten seasons in the National Football League (NFL). He played college football at Tulane and was drafted by the Chicago Bears in the second round of the 2008 NFL Draft. Forte established himself as a dual-threat running back capable of earning yards as a rusher and receiver. He is one of only three players on the "1,000-yard rushing, 100-catch season" club. Forte spent eight seasons with the Bears before playing for the New York Jets for two seasons.

Sean Casey Daigle is a former Major League Baseball pitcher.

David Lee "Trey" Quinn III is an American football wide receiver for the Las Vegas Raiders of the National Football League (NFL). He played college football at LSU and SMU. He was drafted with the final pick of the 2018 NFL Draft by the Washington Redskins, making him that year's Mr. Irrelevant.

Michael Dean Murdock is an American Contemporary Christian singer-songwriter, televangelist and pastor of The Wisdom Center ministry based in Haltom City, Texas. Murdock preaches around the world and is best known for his promotion of prosperity theology. He hosts the School of Wisdom with Mike Murdock television program.

John Wesley was an American actor who worked in many television series, including The Fresh Prince of Bel Air, and in Superhuman Samurai Syber-Squad, where he played the role of Principal Pratchert. He also had roles in many feature films as well as theater productions.

Janet Huckabee is an American politician, the wife of former 2008 and 2016 Republican presidential candidate and former Arkansas governor, Mike Huckabee. She served as the first lady of Arkansas, from July 1996 until January 2007 and oversaw a total remodel of the Arkansas Governor's Mansion, including the addition of the Grand Hall ballroom. Huckabee was also the unsuccessful Republican nominee for Arkansas Secretary of State in 2002.

Michael Ellis DeBakey was a Lebanese-American vascular surgeon and cardiac surgeon, scientist and medical educator who became the chancellor emeritus of Baylor College of Medicine in Houston, Texas, director of the Houston Methodist DeBakey Heart & Vascular Center, and senior attending surgeon at Houston Methodist Hospital in Houston, with a career spanning 75 years.

Elrey Borge Jeppesen was an American aviation pioneer noted for his contributions in the field of air navigation. He created manuals and charts that enabled pilots to fly much more safely. In 1934, he founded the Jeppesen company to sell what he had developed; it is now a subsidiary of Boeing.

William Henson Moore III is an American attorney and businessman who is a former member of the U.S. House of Representatives, having represented Louisiana's 6th congressional district, based about Baton Rouge, from 1975 to 1987. He was only the second Republican to have represented Louisiana in the House since Reconstruction, the first having been David C. Treen, then of Jefferson Parish.