List of Famous people born in Distrito Nacional, Dominican Republic

Ronny Rodríguez Martinez is a Dominican professional baseball infielder for the Hokkaido Nippon-Ham Fighters of Nippon Professional Baseball (NPB). He has played in Major League Baseball (MLB) for the Detroit Tigers. Rodríguez has also played for the Dominican Republic national baseball team.

Enrique Segoviano is a Dominican-born Mexican television producer and director. He is best known as director of Chespirito's various 1970s television series as well as for producing and directing the late 1980s-early 1990s variety series Anabel.

Jean Alain Rodríguez Sánchez is a Dominican lawyer and politician former Attorney General of the Dominican Republic. He was appointed to the position of President Danilo Medina. Before becoming Attorney General, Rodríguez Sánchez served as the executive director of the CEI-RD (2012-2016). He is a member of the Central Committee of the Dominican Liberation Party, the previous governing political party in Dominican Republic until August 16, 2020.

Cuco Valoy is a singer, songwriter, percussionist, Guitarist, who is versatile in salsa, son montuno, Guaracha and merengue musician. He began performing Cuban son with his brother Martín, under the name Los Ahijados. Cuco is the father of Ramón Orlando with whom he formed the band Los Virtuosos, changed to La Tribu. He is widely known for the song Juliana, which was covered by the group DLG; a cover that featured Valoy's vocals.

Maria Milagros Ortiz Bosch is a lawyer, business manager and Dominican politician. She was the first Dominican woman to be vice president of the country, during 2000–2004. She was senator of the Distrito Nacional twice and Secretary of State (Minister) for Education of the Dominican Republic, for the same time period she was vicepresident (2000-2004).

Marcio Veloz Maggiolo was a Dominican writer, archaeologist and anthropologist.

Héctor Manuel Valdez Albizu is the current Governor of the Central Bank of the Dominican Republic, a position he first held from 31 August 1994 through 16 August 2000, and again since 17 August 2004. He is also a well known economist and author of numerous works relating to economics.

Vicente García Guillén is a Dominican musician, singer and composer. He is the former lead singer of the Dominican alternative rock band Calor Urbano, which he left in 2010 to pursue a solo career. Garcia has collaborated in concerts with renowned artists such as Juan Luis Guerra, Alejandro Sanz, Cultura Profetica, Juanes, Ximena Sariñana and Maná among others. He has won three Latin Grammy awards including Best New Artist in 2017.

Arquímedes Euclides Caminero Ordóñez is a Dominican professional baseball pitcher for the Diablos Rojos del México of the Mexican League. He previously played in Major League Baseball (MLB) for the Pittsburgh Pirates, Miami Marlins, and Seattle Mariners. He also played in Nippon Professional Baseball (NPB) for the Yomiuri Giants.

Enny Manuel Romero Hernandez is a Dominican professional baseball pitcher for the Toros de Tijuana of the Mexican League. He previously played in Major League Baseball (MLB) for the Tampa Bay Rays, Washington Nationals, Pittsburgh Pirates and Kansas City Royals and in Nippon Professional Baseball (NPB) for the Chunichi Dragons.