List of Famous people born in Centre-Val de Loire, France

Hélène Robert (1910–1981) was a French film actress.

François Clouet, son of Jean Clouet, was a French Renaissance miniaturist and painter, particularly known for his detailed portraits of the French ruling family.

Philippe Briand is a member of the National Assembly of France. He represents the Indre-et-Loire department, and is a member of The Republicans.

Jacques Bar was a French film producer who made more than 80 films.

Pierre Nicole was one of the most distinguished of the French Jansenists.

Ambrose Maréchal, P.S.S. was an American Sulpician and prelate of the Roman Catholic Church who served as the third Archbishop of the Archdiocese of Baltimore in Maryland. He dedicated the Basilica of the National Shrine of the Assumption of the Blessed Virgin Mary, the oldest cathedral in the United States, in Baltimore in 1821.