List of Famous people born in Castile and León, Spain

Manuel María Arias Domínguez better known as Imanol Arias, is a Spanish actor and film director.

Philip IV was King of Spain from 1621 to his death and King of Portugal from 1621 to 1640. Philip is remembered for his patronage of the arts, including such artists as Diego Velázquez, and his rule over Spain during the Thirty Years' War.

Lucía Jiménez Arranz, is a Spanish actress.

Álvaro Arbeloa Coca is a Spanish retired footballer. He predominantly played as a right back, although he also occasionally played on the left side.

Ángel Nieto Roldán was a Spanish professional Grand Prix motorcycle racer. He was one of the most accomplished motorcycle racers in the history of the sport, winning 13 World Championships and 90 Grand Prix victories in a racing career that spanned twenty-three years from 1964 to 1986. His total of 90 Grand Prix victories ranks him third only to the 122 by Giacomo Agostini, and the 115 for Valentino Rossi. In 2011, Nieto was named an FIM Legend for his motorcycling achievements.

María Soraya Sáenz de Santamaría Antón is a Spanish politician of the People's Party who served as Deputy Prime Minister of Spain and Minister of the Presidency from 2011 to 2018. She was member of the Congress of Deputies representing Madrid from 2004 until 2018.

María del Carmen Fernández de Lomana Gutiérrez, known as Carmen Lomana, is a Spanish businesswoman, television host, socialite and haute couture collector. She is the widow of Guillermo Capdevila, a famous Chilean industrial designer who died in 1999.

Patricia Conde Galindo is a Spanish actress, comedian, TV presenter and model.

Elena Anaya Gutiérrez is a Spanish actress whose career started in 1995. She starred alongside Antonio Banderas in Pedro Almodóvar's The Skin I Live In, for which she won the Goya award for Best Actress. She is also known for her roles in Van Helsing, Habitación en Roma (Room in Rome) and Doctor Poison in Wonder Woman.

Ángela Ruiz Robles was a Spanish teacher, writer, pioneer and inventor of the mechanical precursor to the electronic book. In 1949, Ruiz was awarded Spanish patent 190,698 for the "Mechanical Encyclopedia".