List of Famous people born in Castile and León, Spain

Fernando Álvarez de Toledo y Pimentel, 3rd Duke of Alba, known as the Grand Duke of Alba in Spain and Portugal and as the Iron Duke in the Netherlands, was a Spanish noble, general and diplomat. He was titled the 3rd Duke of Alba de Tormes, 4th Marquess of Coria, 3rd Count of Salvatierra de Tormes, 2nd Count of Piedrahita, 8th Lord of Valdecorneja, Grandee of Spain and a Knight of the Order of the Golden Fleece. His motto in Latin was Deo patrum Nostrorum.

Fernando Martín Álvarez is a Spanish businessman who was the unofficial President of Real Madrid, replacing Florentino Pérez who resigned on 27 February 2006, until he unexpectedly himself resigned on 26 April of the same year. Álvarez was a member of the Real Madrid board of directors under Pérez.

Vasco de Quiroga was the first bishop of Michoacán, Mexico, and one of the judges (oidores) in the second Audiencia that governed New Spain from January 10, 1531, to April 16, 1535.

Inés Sastre Moratón is a Spanish model and actress.

Enrique "Quique" González Casín is a Spanish professional footballer who plays for SD Eibar as a forward.

Henry III of Castile, called the Mourner, was the son of John I and Eleanor of Aragon. He succeeded his father as King of Castile in 1390.

Manuel of Castile (1234 – 25 December 1283, The first Lord of Villena and Peñafiel, Cuéllar, and Escalona, was an Infante, son of Ferdinand III of Castile and his wife Elisabeth of Hohenstaufen.

Gonzalo García Téllez, known as Lalo García was a Spanish basketball player. García played his entire career for CB Valladolid, his hometown club, and played for the Spanish national team.

Julio Velázquez Santiago is a Spanish football manager.

Diego de Deza y Tavera was a theologian and inquisitor of Spain. He was one of the more notable figures in the Spanish Inquisition, and succeeded Tomás de Torquemada to the post of Grand Inquisitor.