List of Famous people born in Antioquia Department, Colombia

Camilo Echeverry, who records as Camilo, is a Colombian singer, songwriter, and producer. Born in Medellín, Camilo is known for his singles "Favorito", "Tutu", alongside Pedro Capó and Shakira, and "Desconocidos", with Mau y Ricky and Manuel Turizo. His music is generally categorized as Latin pop with a mix of urbano and is noted for his romantic lyrics and tenor voice.

Juan Sebastián Marroquín Santos is a Colombian architect, author, and the son of Colombian drug lord Pablo Escobar.

Juan Luis Londoño Arias, known professionally as Maluma, is a Colombian singer, songwriter, and actor signed to Sony Music Colombia, Sony Latin and Fox Music. Musically, Maluma's songs have been described as reggaeton, Latin trap, and pop. Born and raised in Medellín, he developed an interest in music at a young age, and began recording songs at the age of 16. He released his debut album, Magia, a year later in 2012. However, his breakthrough album was 2015's Pretty Boy, Dirty Boy, which led to successful collaborations with several artists. He released F.A.M.E. in 2018, to further commercial success. He followed it up with 11:11 in 2019, and Papi Juancho, released without further announcement in 2020. His single "Hawái" reached number three on the Billboard Global 200, and became the first number one single on the Billboard Global Excl. U.S. chart. With sales of over 26 million records, Maluma is one of the best-selling Latin music artists.

Carolina Giraldo Navarro, known professionally as Karol G, is a Colombian singer and songwriter. She is predominantly described as a reggaeton and Latin trap artist, but has experimented with a variety of other genres including reggae and sertaneja. She is also noted for her prominent female presence in the reggaeton scene. In 2018, she won the Latin Grammy Award for Best New Artist, and has been nominated for several Billboard Latin Music Awards and Premios Lo Nuestro awards.

José Álvaro Osorio Balvín, better known as J Balvin, is a Colombian reggaeton singer and songwriter. He has been referred to as the "Prince of Reggaeton", and is one of the best-selling Latin music artists with sales of more than 35 million records worldwide. Balvin was born in Medellín, Colombia. At age 17, he moved to the United States to learn English, where he lived in both Oklahoma and New York. He then returned to Medellín and gained popularity performing at clubs in the city.

Héctor Abad Faciolince is a Colombian novelist, essayist, journalist, and editor. Abad is considered one of the most talented post-Latin American Boom writers in Latin American literature. Abad is best known for his bestselling novel Angosta, and more recently, El Olvido que Seremos.

Carla Evelyn Giraldo Quintero is a Colombian actress, model and singer.

Dandeny Muñoz Mosquera, also known as "La Quica", is a Colombian former hitman for the Medellín Cartel, a drug trafficking group. He was described as at one point being the "chief assassin" for the Cartel's leader Pablo Escobar.

Sebastián Obando Giraldo, known professionally as Sebastián Yatra, is a Colombian singer and songwriter. He began as a Latin pop artist and has recorded many ballads, but has released several successful reggaeton singles. Yatra is noted for his romantic lyrics, melding traditional lyricism with modern reggaeton influences. He rose to prominence in Latin America in 2016 when he released the hit "Traicionera". He has released two studio albums and recorded with artists from a diverse range of musical genres throughout his career.

David Ospina Ramírez is a Colombian professional footballer who plays as a goalkeeper for Serie A club Napoli and the Colombia national team.