List of Famous people with last name Isaac

Óscar Isaac Hernández Estrada is a Guatemalan-American actor who starred in the tragicomedy Inside Llewyn Davis (2013), for which he received a Golden Globe Award nomination, the crime drama A Most Violent Year (2014), and the science fiction thriller Ex Machina (2014). In 2006, he portrayed Saint Joseph, husband of Mary, in The Nativity Story. He also portrayed José Ramos-Horta, former president of East Timor and co-recipient of the 1996 Nobel Peace Prize, in the Australian film Balibo, for which he won the AACTA Award for Best Actor in a Supporting Role.

Jonathan Judah Isaac is an American professional basketball player for the Orlando Magic of the National Basketball Association (NBA). He played college basketball for one season for the Florida State Seminoles. He was selected by Orlando in the first round of the 2017 NBA draft with the sixth overall pick.

Elisapie Isaac is a Canadian Inuk singer-songwriter, broadcaster, documentary filmmaker, and activist. She spent her childhood in Salluit, Nunavik, and moved to Montreal in 1999 to pursue communication studies in order to become a journalist.

The biblical patriarch Isaac is recognized as a prophet and messenger of God by Muslims. As in Judaism and Christianity, Islam maintains that Isaac was the son of the patriarch and prophet Abraham from his wife Sarah. Muslims hold Isaac in deep veneration because they believe that both Isaac and his older half-brother Ishmael continued their father's spiritual legacy through their subsequent preaching of the message of God after the death of Abraham. Isaac is mentioned in fifteen passages of the Quran. Along with being mentioned several times in the Quran, Isaac is held up as one of Islam's prophets.

Jules Isaac was "a well known and highly respected Jewish historian in France with an impressive career in the world of education" by the time World War II began.

James Isaac was an American film director and visual effects supervisor.

George Ishak is an Egyptian politician and activist. During the later part of Hosni Mubarak's presidency, he co-founded the grassroots Kefaya opposition movement.