List of Famous people born in Sicily, Italy

Luca Guadagnino is an Italian filmmaker. He has collaborated a number of times with actress Tilda Swinton, including on the films The Protagonists (1999), I Am Love (2009), A Bigger Splash (2015) and Suspiria (2018), a remake of the 1977 film of the same name.

Colonel Luca Parmitano is an Italian astronaut in the European Astronaut Corps for the European Space Agency (ESA). He was selected as an ESA astronaut in May 2009. Parmitano is also a Colonel and test pilot for the Italian Air Force. Parmitano is the youngest non-Russian astronaut to undertake a long-duration mission, at 36 years and eight months old on the launch day of his mission.

Alfredo Donnarumma is an Italian professional footballer who plays as a forward or attacking midfielder for Serie B club Brescia.

Miriam Leone is an Italian actress and beauty pageant titleholder who won the Miss Italia 2008 beauty contest.

Damiano Caruso is an Italian professional road bicycle racer, who currently rides for UCI WorldTeam Team Bahrain Victorious. Caruso was also the 2008 under-23 Italian national champion for the road race.

Deborah Salvatrice Blando is an Italian-born Brazilian singer and composer. She has sold about six million copies sold worldwide, with six albums released between 1991 and 2002. She has seven number 1 single and ten Top 10 singles in Brazil, five singles in the American Hispanic market, and two of them in the Top 10 which became known in Europe, such as the pop ballad "Innocence" in 1992.

Maria Grazia Cucinotta is an Italian actress who has featured in films and television series since 1990. She has also worked as a film producer, screenwriter and model. Internationally she is best known for her roles in Il Postino, as Isabella from HBO television series The Sopranos, and as the Bond girl, credited as a Cigar Girl, in the James Bond film The World Is Not Enough.

C. Marcella Carollo worked as a professional astronomer for 25 years between 1994–2019. Her scientific career was ended by the ETH Zürich who, following accusations that she had bullied students, made her the first Professor to be dismissed at ETH Zurich in the 165 years of its history. Carollo has maintained her innocence against these accusations, publicly commenting on her case in terms that indicate "academic mobbing". The dismissal has been appealed to the Swiss Federal Administrative Court.

Giuseppe Tornatore is an Italian film director and screenwriter. He is considered as one of the directors who brought critical acclaim back to Italian cinema. In a career spanning over 30 years he is best known for directing and writing drama films such as Everybody's Fine, The Legend of 1900, Malèna, Baarìa and The Best Offer. Probably his most noted film is Nuovo Cinema Paradiso, for which Tornatore won the Academy Award for Best Foreign Language Film. He has also directed several advertising campaigns for Dolce & Gabbana.

Gerlando Buzzanca, best known as Lando Buzzanca, is an Italian theatrical, film and television actor, whose career spanned over 55 years.