List of Famous people born in Santa Fe Province

Lionel Andrés Messi is an Argentine professional footballer who plays as a forward and captains both the Spanish club Barcelona and the Argentina national team. Often considered as the best player in the world and widely regarded as one of the greatest players of all time, Messi has won a record six Ballon d'Or awards and a record six European Golden Shoes. He has spent his entire professional career with Barcelona, where he has won a club-record 33 trophies, including ten La Liga titles, four UEFA Champions League titles and six Copas del Rey. A prolific goalscorer and creative playmaker, Messi holds the records for most goals in La Liga (455), a La Liga and European league season (50), most hat-tricks in La Liga (36) and the UEFA Champions League (8), and most assists in La Liga (185), a La Liga and European league season (21) and the Copa América (12). He has scored over 700 senior career goals for club and country.

Ernesto "Che" Guevara was an Argentine Marxist revolutionary, physician, author, guerrilla leader, diplomat, and military theorist. A major figure of the Cuban Revolution, his stylized visage has become a ubiquitous countercultural symbol of rebellion and global insignia in popular culture.

Mauro Emanuel Icardi is an Argentine professional footballer who plays as a striker for Ligue 1 club Paris Saint-Germain and the Argentina national team.

Maximiliano Rubén "Maxi" Rodríguez is an Argentine footballer who plays for Newell's Old Boys. Nicknamed La Fiera, he is commonly used as a winger on both flanks but can also operate as an attacking midfielder.

Lionel Sebastián Scaloni is an Argentine retired footballer, and the current manager of the Argentina national team. A player of wide range, he operated as a right back or right midfielder.

Ángel Fabián Di María is an Argentine professional footballer who plays for French Ligue 1 club Paris Saint-Germain and the Argentina national team. He can play as either a winger or attacking midfielder.

Nicole Denise Cucco, known professionally as Nicki Nicole, is an Argentine rapper and singer. Born and raised in Rosario, Santa Fe, she gained popularity with her singles "Wapo Traketero", "Colocao", "Mamichula", and "Mala Vida".

Jorge Luis Sampaoli Moya is an Argentine football manager who currently manages Clube Atlético Mineiro. Sampaoli started out as a youth player and eventually switched to management after a severe injury. Sampaoli started with an impressive managerial run at Coronel Bolognesi of Peru in 2004, and continued with brief but successful terms at O'Higgins of Chile and Emelec of Ecuador.

Marcelo Alberto Bielsa Caldera is an Argentine professional football manager and the current head coach of Premier League club Leeds United. He is also a former player and played as a defender for Newell's Old Boys, Instituto de Córdoba, and Argentino de Rosario.

Santiago Hernán Solari Poggio is an Argentine professional football manager and former player who played as a left midfielder and is currently the manager of Mexican side Club América.