List of Famous people born in San Pedro de Macorís, Dominican Republic

Samuel Peralta Sosa is a Dominican American former professional baseball right fielder of Haitian descent. He played in Major League Baseball (MLB) for 19 seasons, primarily with the Chicago Cubs. After playing for the Texas Rangers and Chicago White Sox, Sosa joined the Cubs in 1992 and became regarded as one of the game's best hitters. Sosa hit his 400th home run in his 1,354th game and his 5,273rd at-bat, reaching this milestone quicker than any player in National League history. He is one of nine players in MLB history to hit 600 career home runs.

Fernando Gabriel Tatís Medina, nicknamed "El Niño", is a Dominican professional baseball shortstop for the San Diego Padres of Major League Baseball (MLB). He made his MLB debut in 2019.

Johnny Cueto Ortiz is a Dominican professional baseball pitcher for the San Francisco Giants of Major League Baseball (MLB). Cueto signed in 2004 as an undrafted amateur free agent. He previously played for the Cincinnati Reds from 2008 through 2015, and the Kansas City Royals in 2015. He was traded by the Reds to the Royals during the 2015 season, and helped the Royals win the World Series.

Robinson José Canó is a Dominican professional baseball second baseman for the New York Mets of Major League Baseball (MLB). He previously played for the New York Yankees from 2005 to 2013, and for the Seattle Mariners from 2014 to 2018. Canó has represented the Dominican Republic in international play, including winning both the gold medal and Most Valuable Player Award (MVP) of the 2013 World Baseball Classic (WBC) tournament.

Fernando Gabriel Tatís Sr. is a Dominican former professional baseball third baseman, and a current manager in Minor League Baseball. Over his 11-year Major League Baseball (MLB) career, he played for the Texas Rangers, St. Louis Cardinals, Montreal Expos, Baltimore Orioles, and the New York Mets. Tatis holds the major league record for RBIs in an inning, a feat that he achieved by hitting two grand slams in one inning during a game on April 23, 1999, becoming the only player in MLB history ever to do so.

Miguel Ángel Jean Sanó is a Dominican professional baseball infielder for the Minnesota Twins of Major League Baseball (MLB). He made his MLB debut on July 2, 2015, and was an All-Star in 2017. Sanó has played for most of his career as a third baseman, but has played more first base in 2018 and 2019, and with the Twins signing Josh Donaldson on January 14, 2020, is anticipated to be the Twins' starting first baseman starting in the 2020 season.

Pedro Guerrero is a Dominican former professional baseball player. He played all or part of fifteen seasons in Major League Baseball from 1978 to 1992 with the Los Angeles Dodgers and St. Louis Cardinals.

Bryan De Jesus Rodriguez Guillen is a Dominican Republic professional baseball pitcher for the Hokkaido Nippon-Ham Fighters of Nippon Professional Baseball (NPB).

Xavier Alexander Batista is an Dominican professional baseball outfielder for the Hiroshima Toyo Carp of Nippon Professional Baseball.

Alfonso Guilleard Soriano is a Dominican former professional baseball left fielder and second baseman. He played in Major League Baseball (MLB) for the New York Yankees, Chicago Cubs, Texas Rangers, and Washington Nationals, and in Nippon Professional Baseball for the Hiroshima Toyo Carp.