List of Famous people born in Pennsylvania, United States of America

Victor Bailey was an American bass guitar player. He was the bassist for Weather Report during their final years from 1982 to 1986, and launched a solo career in 1988. As a musician, Bailey was known for his signature scat-bass solos.

Johannes Peter "Honus" Wagner, sometimes referred to as "Hans" Wagner, was an American baseball shortstop who played 21 seasons in Major League Baseball from 1897 to 1917, almost entirely for the Pittsburgh Pirates. Wagner won his eighth batting title in 1911, a National League record that remains unbroken to this day, and matched only once, in 1997, by Tony Gwynn. He also led the league in slugging six times and stolen bases five times. Wagner was nicknamed "The Flying Dutchman" due to his superb speed and German heritage. This nickname was a nod to the popular folk-tale made into a famous opera by another Wagner.

Aimee Mullins is an American athlete, actress, and public speaker. She was born with a medical condition that resulted in the amputation of both of her lower legs. She is famous for being the first amputee to compete against able-bodied athletes in National Collegiate Athletic Association events, and competed in the Paralympics in 1996 in Atlanta. In 1999 she began modeling, and in 2002 she began an acting career. She speaks at conferences, and is well known for her TED talks.

Col. James Benson Irwin, USAF was an American astronaut, aeronautical engineer, test pilot, and a United States Air Force pilot. He served as Apollo Lunar Module pilot for Apollo 15, the fourth human lunar landing. He was the eighth person to walk on the Moon and the first, and youngest, of those astronauts to die.

Robert Charles Sproul was an American Reformed theologian and ordained pastor in the Presbyterian Church in America. He was the founder and chairman of Ligonier Ministries and could be heard daily on the Renewing Your Mind radio broadcast in the United States and internationally. Under Sproul's direction, Ligonier Ministries produced the Ligonier Statement on Biblical Inerrancy, which would eventually grow into the 1978 Chicago Statement on Biblical Inerrancy, of which Sproul, alongside Norman Geisler, was one of the chief architects. Sproul has been described as "the greatest and most influential proponent of the recovery of Reformed theology in the last century."

Patrick Durkin Cummins is an American retired mixed martial artist who formally competed in the Light heavyweight division of the Ultimate Fighting Championship. A professional competitor since 2010, he has formerly competed for Strikeforce.

Doris A. Smith, known professionally as Toukie Smith is an American actress and model. Smith is best known for her role as Eva Rawley on the NBC sitcom 227 (1989–90). She is the sister of fashion designer Willi Smith.

Marc Lamont Hill is an American academic, author, activist, and television personality. He is a professor of media studies and urban education at Temple University in Philadelphia, Pennsylvania.

Timothy Richard Heidecker is an American comedian, writer, director, actor, and musician. He is best known as one half of the comedy duo Tim & Eric, along with Eric Wareheim. They are noted for creating the television shows Tom Goes to the Mayor, Tim and Eric Awesome Show, Great Job!, and Tim & Eric's Bedtime Stories.

Michaela Conlin is an American actress, best known for her role as Angela Montenegro on the Fox crime procedural comedy-drama Bones.