List of Famous people born in Ōsaka Prefecture, Japan

Takahiro Shiomi is a Japanese professional baseball pitcher for the Tohoku Rakuten Golden Eagles in Japan's Nippon Professional Baseball.

Chieko Asakawa is a blind Japanese computer scientist, known for her work at IBM Research – Tokyo in accessibility. A Netscape browser plug-in she developed, the IBM Home Page Reader, became the most widely used web-to-speech system available. She is the recipient of numerous industry and government awards.

Mizuho Sakaguchi is a Japanese football player. She plays for Tokyo Verdy Beleza. She also plays for the Japan national team.

Aya Nakahara is a Japanese manga artist. She won the 49th Shogakukan Manga Award for shōjo manga for Lovely Complex a.k.a. Love Com, a romance manga about a tall high school girl who falls in love with a short guy.

Sonoda Kenichi is a manga artist and animation character designer.

Shiori Kanzaki is a Japanese actress. She is best known for playing Yuka Sanada in Genseishin Justirisers.

Ryoji Morimoto is a Japanese actor who is affiliated with both Artist Box and Fireworks. He graduated from Osaka Municipal Sakuranomiya High School's Physical Education.

Hyuma Matsui is a Japanese former baseball player. He has played in Nippon Professional Baseball (NPB) for the Yokohama DeNA BayStars.

Naoto Nishida is a professional baseball player, and an infielder for the Hanshin Tigers, a team in Japan's Nippon Professional Baseball League.

Satoru Kōsaki is a Japanese music composer and arranger. He is best known for his work on anime, including Lucky Star, The Melancholy of Haruhi Suzumiya, Monogatari and Beastars. He began his career in 1999 at Namco, where he primarily composed soundtracks for video games. Since 2005, he has been affiliated with Keiichi Okabe's music production company Monaca, where he has often collaborated with his colleagues to produce soundtracks for anime and other media.