List of Famous people born in Ōsaka Prefecture, Japan

Fuminori Ujihara is a Japanese comedian best known as the tsukkomi half of a popular owarai duo Rozan　(ロザン) alongside Hirofumi Suga. Given his 158 IQ score, bachelor's degree in law from Kyoto University, and championship titles from a number of TV quiz shows, he is also widely known as one of the most intelligent comedians in Japan. He is 177 cm tall and weighs 59 kg.

Yoshiaki Murakami is a Japanese investor, bull, former bureaucrat of the MITI, co-founder of "Mirakami Fund", and founder of the Murakami Family Foundation (村上財団).

Rika Kakiuchi , previously known by her stage name, Rina Aiuchi and now professionally known as R, is a Japanese singer, songwriter and entrepreneur. Born in Higashiōsaka, Japan, she won the first season of the audition Super Starlight Contest, winning a recording contract with Giza Studio. Her eurobeat-sounding debut album, Be Happy (2001) was certified gold in Japan and spawned a top-five single, "Koi wa Thrill, Shock, Suspense", which served as the theme song to the Japanese anime television series Case Closed. Aiuchi's second album Power of Words became her best-selling album, selling over 419,000 copies nationwide and certificated platinum in Japan.

Satoshi Matsuda is a Japanese actor who has appeared in a number of feature films and television series. He is affiliated with Sun Music Production.

Tadao Ando is a Japanese self-taught architect whose approach to architecture and landscape was categorized by architectural historian Francesco Dal Co as "critical regionalism". He is the winner of the 1995 Pritzker Prize.

Genyo Takeda is a retired Japanese game designer and executive who worked for the video game company Nintendo. Takeda was formerly the general manager of Nintendo's Integrated Research & Development division, and was the co-representative director and "Technology Fellow" of the company until his retirement in 2017.

Asuka Hayashi is a Japanese singer who debuted at the age of 13 in January 2003 in Japan and Taiwan.

Yoshitomo Tani is a former Japanese professional baseball player from Higashiōsaka, Osaka, Japan. He played as an outfielder for the Orix Buffaloes and Yomiuri Giants. He holds the Pacific League record for hits in a single season by a right-handed batter with 189 hits in 2003 for Orix. He also holds the Japanese NPB record for doubles in a single season with 52 in 2001.

Kendo Kobayashi is a Japanese comedian and actor. His real and former stage name is Tomoharu Kobayashi . He is nicknamed Ken Koba (ケンコバ), Koba (コバ), and Mr. Yaritai Hōdai . He is represented with Yoshimoto Creative Agency of Yoshimoto Kogyo in Tokyo. He graduated from the Yoshimoto New Star Creation (NSC) in Osaka.

Tomohiro Nishikado is a Japanese video game developer. He is best known as the creator of the fixed shooter Space Invaders, released to the public in 1978 by the Taito of Japan, often credited as the first shoot 'em up and for beginning the golden age of video arcade games. Originally Nishikado wanted to use airplanes as enemies for Space Invaders, but would have encountered problems making them move smoothly due to the limited computing power at the time. Humans would have been easier to render, but management at Taito forbade the use of human targets.