List of Famous people born in New York City, United States of America

Kenneth "Supreme" McGriff is an American convicted former drug lord and gangster from Queens, New York, United States.

William Patrick Polian Jr. is an American football executive. He rose to league prominence as the General Manager of the Buffalo Bills, building a team that participated in four straight Super Bowls—the most consecutive appearances by any team—but lost each time. Following his stint in Buffalo, Polian went on to become the General Manager of the expansion Carolina Panthers. He then served as President and General Manager of the Indianapolis Colts of the National Football League from 1998 to 2011, where they reached two Super Bowls, winning XLI. He subsequently served as an NFL analyst for ESPN. Polian was elected to the Pro Football Hall of Fame in 2015. In 2018, Polian co-founded the now-defunct Alliance of American Football.

Dennis Anthony Tito is an American engineer and entrepreneur, most widely known as the first space tourist to fund his own trip into space. In mid-2001, he spent nearly eight days in orbit as a crew member of ISS EP-1, a visiting mission to the International Space Station. This mission was launched by the spacecraft Soyuz TM-32, and was landed by Soyuz TM-31.

Sholam Weiss is an American former businessman and convicted fraudster.

Vanessa Estelle Williams, sometimes professionally credited as Vanessa A. Williams, is an American actress and producer. She is best known for her roles as Maxine Joseph–Chadway in the Showtime drama series, Soul Food (2000–04), for which she received NAACP Image Award for Outstanding Actress in a Drama Series and as Nino Brown's feisty gun moll, Keisha in the 1991 crime drama film, New Jack City. Williams also is known for her role as Anne-Marie McCoy in the first and fourth films in the Candyman film series, and as Rhonda Blair in the first season of the Fox prime time soap opera, Melrose Place (1992–93).

Richard Perry is an American record producer. Perry began as a performer in his adolescence, but shifted gears after graduating from college and rose through the late 1960s and early 1970s to become a highly successful and popular record producer with over a dozen gold records to his credit by 1982. From 1978 to 1983, he ran his own record label, Planet Records, which scored a string of hits with the main act on its roster, pop/R&B group The Pointer Sisters. After Planet's sale to RCA Records, Perry continued his work in the music industry as an independent producer. With hit records stretching from the 1960s through the 2000s, his more successful modern releases include albums by Rod Stewart and Carly Simon.

Domenico "Domenick" Lombardozzi is an American actor from the Bronx, New York. He portrayed Herc in The Wire and is also known for his roles in A Bronx Tale (1993), Entourage, and The Irishman (2019).

Susan Kelechi Watson is an American actress. She is known for her work on the television show Louie and for her role as Beth Pearson in This Is Us. She was nominated for the Critics' Choice Television Award for Best Supporting Actress in a Drama Series for the latter.

George Maharis is an American actor who portrayed Buz Murdock in the first three seasons of the TV series Route 66. Maharis also recorded numerous pop music albums at the height of his fame, and later starred in the short-lived TV series The Most Deadly Game.

James Butler Jr. is an American former professional boxer who competed from 1996 to 2004. He challenged once for the IBF super middleweight title in 2000, but he is best known for his infamous bout on November 23, 2001. Butler brutally sucker punched Richard Grant after losing the fight and served four months at Rikers Island. In 2004, Butler was arrested for the murder of Sam Kellerman and was sentenced to 29 years and four months in prison.