List of Famous people born in Greensboro, United States of America

John Robert Isner is an American professional tennis player who has been ranked as high as No. 8 in men's singles by the Association of Tennis Professionals (ATP). Considered one of the best servers ever to play on the ATP Tour, Isner achieved his career-high singles ranking in July 2018 by virtue of his maiden Masters 1000 crown at the 2018 Miami Open and a semifinals appearance at the 2018 Wimbledon Championships. He has also twice reached the quarterfinals at the US Open in 2011 and 2018, the latter of which helped qualify him for his first ATP Finals appearance later that year. He currently has the second-most aces in the history of the ATP Tour, having served over 12,000 aces. At the 2010 Wimbledon Championships, he played the longest professional tennis match in history, defeating Nicolas Mahut in a total of 11 hours and 5 minutes, played over the course of three days. Isner currently holds the record for hitting the ATP's fastest "official" serve ever and third-fastest on record in tennis at 157.2 mph or 253 km/h during his first-round 2016 Davis Cup match.

Loretta Elizabeth Lynch is an American lawyer who served as the 83rd attorney general of the United States from 2015 to 2017. She was appointed by President Barack Obama to succeed Eric Holder and previously served as the United States Attorney for the Eastern District of New York under both Presidents Bill Clinton (1999–2001) and Obama (2010–2015). As a U.S. attorney, Lynch oversaw federal prosecutions in Brooklyn, Queens, Staten Island, and Long Island.

Frederick "Curly" Neal was an American basketball player who played with the Harlem Globetrotters. Following in the footsteps of Marques Haynes, Neal became the Trotters' featured ballhandler, a key role in the team's exhibition act.

Rhiannon Giddens is an American musician. She is a founding member of the country, blues and old-time music band Carolina Chocolate Drops, where she is the lead singer, fiddle player, and banjo player.

Hamilton Nash Grier is an American Internet personality. He became known for his online videos on the now-defunct video sharing service Vine in early 2013. By 2015, Grier was the second most-followed user on the platform.

Carolyn Bosher Maloney is an American politician serving as the U.S. Representative for New York's 12th congressional district since 2013, and previously for New York's 14th congressional district since 1993. The district, numbered as the 14th congressional district from 1993 until redistricting in 2013, includes most of Manhattan's East Side, Astoria and Long Island City in Queens, Greenpoint, Brooklyn, as well as Roosevelt Island. She is a member of the Democratic Party.

Jeffrey Keith Varner is a former American real estate agent and television personality, a news anchor and reporter, a former entertainment reporter, and a veteran contestant on three seasons of the CBS reality television series, Survivor: The Australian Outback, Survivor: Cambodia, and Survivor: Game Changers.

Whitney Way Thore is an American television personality best known for her appearances on the television show My Big Fat Fabulous Life, which airs on TLC.

Abel Nazario Trujillo is an American mixed martial artist who most recently competed in the Lightweight division of the Ultimate Fighting Championship.

Keenan Alexander Allen is an American football wide receiver for the Los Angeles Chargers of the National Football League (NFL). He played college football for the California Golden Bears before leaving after his junior year. He was drafted by the Chargers in the third round of the 2013 NFL Draft. Allen won multiple rookie honors after setting Chargers' records for receptions and receiving yards by a rookie. In 2017, he was named the NFL Comeback Player of the Year.