List of Famous people born in Granma Province, Cuba

Laura Inés Pollán Toledo was a prominent Cuban opposition leader. Pollan founded the dissident group Ladies in White, which holds pacific protest marches with the wives and spouses of political prisoners in Cuba to demand their release.

Yoenis Céspedes Milanés, nicknamed La Potencia, is a Cuban-born professional baseball outfielder who is a free agent. He made his Major League Baseball (MLB) debut on March 28, 2012, for the Oakland Athletics, and has also played in MLB for the Boston Red Sox, Detroit Tigers and New York Mets. Primarily a left fielder in his early career, he has split between left and center field since joining the Mets. A right-hand batter and fielder, he stands 5 feet 10 inches (1.78 m) tall and weighs 220 pounds (100 kg).

Carlos Manuel de Céspedes del Castillo was a Cuban revolutionary hero. Cespedes, who was a plantation owner in Cuba, freed his slaves and made the declaration of Cuban independence in 1868 which started the Ten Years' War (1868–78), which ultimately led to Cuban independence.

Tomás Estrada Palma was a Cuban politician and the first President of Cuba. Initially he was the President of the Cuban Republic in Arms during the Ten Years' War and again between May 20, 1902 and September 28, 1906. His collateral career as a New York City Area Educator and writer enabled Estrada Palma to create Pro-Cuban literature aimed at gaining sympathy, assistance and publicity. He was eventually successful in garnering the attention of influential Americans. He was an early and persistent voice calling for the United States to intervene in Cuba on humanitarian grounds. He was the first President of Cuba, between May 20, 1902 and September 28, 1906. During his presidency his major accomplishments include improving Cuba's infrastructure, communication, and public health.

Blas Roca Calderio was a Cuban politician and Marxist theorist who served as President of the National Assembly of People's Power in Cuba from 1976 to 1981. He was also head of the pre-1959 revolution Communist Party of Cuba for 28 years and editor of the communist newspaper Hoy. He was a signatory of the Cuban Constitution of 1940 and chaired the committee that wrote the country's first socialist constitution in 1976.

Pedro Felipe Figueredo, mostly known as Perucho was a Cuban poet, musician, and freedom fighter of the 19th century. In the 1860s, he was active in the planning of the Cuban uprising against the Spanish known as the Ten Years' War.

Archbishop Francis Mansour Zayek was a prelate of the Maronite Church. He was the founding eparch of the Maronite Catholic Eparchy of Saint Maron of Brooklyn, an Eastern Catholic diocese based in Brooklyn, New York, which covers the eastern coast of the United States.