List of Famous people born in Columbus, United States of America

Linda Powell is an American actress.

Laura Jane Grace is an American musician best known as the founder, lead singer, songwriter and guitarist of the punk rock band Against Me!. In addition to Against Me!, Grace fronts the band Laura Jane Grace & The Devouring Mothers, a solo project she started in 2016. Grace is notable for being one of the first highly visible punk rock musicians to come out as transgender, after she publicly came out in May 2012.

Beryl Alaine Howell is the Chief United States District Judge of the United States District Court for the District of Columbia. She was a federal judge supervising the grand jury for special counsel Robert Mueller's probe into Russian interference in the 2016 United States elections.

William Philip Gramm is an American economist and politician who represented Texas in both houses of Congress. Though he began his political career as a Democrat, Gramm switched to the Republican Party in 1983.

Timothy "Tim" A. Springer, Ph.D. is an immunologist and Latham Family Professor at Harvard Medical School. Springer is best known for his pioneering work in discovering the first integrins and intercellular adhesion molecules (ICAMs) and elucidating how these cell adhesion molecules function in the immune system. His innovative use of monoclonal antibodies in his research paved the way for the development of therapeutic antibodies, known as selective adhesion molecule inhibitors, to treat autoimmune diseases. In recent years, Springer's research interest has expanded to include malaria, transforming growth factor beta (TGF-β) signaling molecules, and von Willebrand factor.

Tracy Reed is an American actress.