List of Famous people born in Castile and León, Spain

Francisco Igea Arisqueta is a Spanish politician of the Citizens party. A doctor by profession, he led the party in the 2019 Castilian-Leonese regional election, and became vice president of the Junta of Castile and León after forming a government with the People's Party leader Alfonso Fernández Mañueco. In the 2022 election, his party lost all their seats except his own. He was previously a member of the Congress of Deputies (2015–2019) and came runner-up in his party's 2020 leadership election.

Íñigo Cuesta López de Castro is a Spanish former professional road bicycle racer, who now works as a directeur sportif for UCI Women's Continental Team Burgos Alimenta Women Cycling Sport.

José Manuel López Rodríguez is a former Spanish cyclist. He competed in the individual road race and team time trial events at the 1964 Summer Olympics. He rode in 7 editions of the Vuelta a España and four times in the Tour de France.

Rafael Palmero Ramos was a Spanish Roman Catholic prelate.