List of Famous people born in Castile and León, Spain

Infante Henry of Aragon, 1st Duke of Villena, 4th Count of Alburquerque, Count of Ampurias, was the Grand Master of the Order of Santiago.

Antonio Tovar Llorente was a Spanish philologist, linguist and historian.

Charles, Prince of Viana, sometimes called Charles IV of Navarre, was the son of King John II of Aragon and Queen Blanche I of Navarre.

Tomás Luis de Victoria was the most famous composer in 16th-century Spain, and was one of the most important composers of the Counter-Reformation, along with Giovanni Pierluigi da Palestrina and Orlando di Lasso. Victoria was not only a composer but also an accomplished organist and singer as well as a Catholic priest. However, he preferred the life of a composer to that of a performer.

María Concepción Paredes Tamayo was a Spanish athlete who specialised in the triple jump. She represented her country at the 1996 Summer Olympics, as well as three outdoor and four indoor World Championships.

John II of Castile was King of Castile and León from 1406 to 1454.

Alfonso de Aragon y Escobar (1417–1495), Duke of Villahermosa, Count of Ribagorza and Cortes and Grand Master of the Order of Calatrava, was an illegitimate son of John II of Aragon and one of his mistresses, Leonor de Escobar, daughter of Alfonso Rodríguez de Escobar.

Daniel Navarro García is a Spanish professional road bicycle racer, who most recently rode for UCI WorldTeam Israel Start-Up Nation.

Isabella of Castile (1283–1328) was the Queen of Aragon as the first wife of King James II and Duchess of Brittany as the second wife of Duke John III.

García Fernández, called of the White Hands, was the count of Castile and Alava from 970 to 995. In May 995, he was captured by a raiding party while out hunting. Wounded in the encounter, he was sent to Cordoba as a trophy, but died at Medinaceli in June 995.