List of Famous people born in Bourgogne-Franche-Comté, France

Honoré Jacquinot was a French surgeon and zoologist. Jacquinot was the younger brother of the naval officer Charles Hector Jacquinot, and sailed with him as a surgeon and naturalist on La Zelée on Dumont d'Urville's Astrolabe expedition (1837–1840).

Jean Kaltenbach was a French politician. A member of the Rally for the Republic, he served as President of the Regional Council of Champagne Ardenne from 1988 to 1998.

Jean Hermil was Roman Catholic bishop of Viviers, France.

Jean-Paul Hosotte is a French racing cyclist. He rode in the 1981 Tour de France.

Alexandre Beaupain, known as Alex Beaupain, born 15 October 1974 in Besançon, is a French singer and composer, both of his own songs, and of the music and songs for films, particularly those directed by Christophe Honoré. He has released several albums and received awards, both for film scores and the song albums.

André Billardon is a French politician and member of the Socialist Party. He is the current mayor of Le Creusot and used to be a Minister during Pierre Bérégovoy's term of office, while François Mitterrand was president. Billardon was a mathematics teacher prior to his involvement in local politics in the third circonscription of Saône-et-Loire. Thus, he was elected as a député for the first time in 1978. He was then re-elected in every legislative election until 1992. He was then appointed Minister for the Energy. He carried out his duties from October 1992 to March 1993. He was again elected as a député in June 1997, until May 2002. He also used to be the chairman of the Communauté Urbaine Le Creusot - Montceau.

Christophe Deloire is a French NGO leader, author, and publisher.