List of Famous people who died at 21

Sandro Barbosa do Nascimento was the perpetrator of the Bus 174 hostage crisis in Jardim Botânico, Rio de Janeiro, Brazil. Nascimento boarded a public bus, intending to rob the passengers. However, the incident developed into a hostage situation, which was broadcast live by most Brazilian national television channels.

The Tour of the Gila is a cycling stage race for both men and women located in New Mexico, United States. It is sponsored by the component maker SRAM. The "Gila" began in 1987. Beginning in 2012, the men's Gila has been added to the UCI America Tour as a UCI classification 2.2 stage race, which permits UCI ProTeams to enter if they so choose; beginning in 2015, the women's Gila has also been added to the women's UCI international tour as a UCI classification 2.2 stage race.

Eduard Andrés Gutiérrez Castillo was a Colombian professional footballer who played for Atlético Huila as a defender. He died in a road traffic accident at the age of 21.

Michel Edouard Brière was a Canadian professional ice hockey player for one season in the National Hockey League (NHL). Following his rookie season with the Pittsburgh Penguins, Brière was involved in a car accident in which he suffered major head trauma. After multiple brain surgeries and 11 months in a coma, he died as a result of his injuries at the age of 21.

Anatoli Yevgenyevich Kozhemyakin was a Soviet football player. He died in a freak accident: he was stuck in an elevator, but was able to open the elevator doors, as he tried to climb out, the elevator started moving again and crushed him to death.

Emed Akel also spelled Imad Akel was a commander of the Izz al-Din al-Qassam Brigades, the military wing of Hamas. He was killed at age 22 by Israeli forces outside a house where he was hiding in 1993. In July 2009, Hamas released its first film, a two-hour biopic celebrating the life and martyrdom of Akel. The film was written by Hamas strongman Mahmoud al-Zahar and the interior minister, Fathi Hamad.

Anastasia Igorevna Berezina was a Russian football player. She was a midfielder who played for the Chertanovo football club and the Russian National under 19 team. She died of cardiac arrest in her sleep at the age of 22.

Mahicon José Librelato da Silva, was a Brazilian footballer.

Vanessa Duriès, also known as Katia Lamara, was a French novelist.

Yuri Nikolayevich Raevsky (1952–1973), also known as The Vnukovo Maniac, was a Soviet rapist and serial killer.