List of Famous people born in South Holland, Kingdom of the Netherlands

Laurien van der Graaff is a Swiss cross-country skier.

Jacobus Henricus "Henry" van 't Hoff Jr. was a Dutch physical chemist. A highly influential theoretical chemist of his time, Van 't Hoff was the first winner of the Nobel Prize in Chemistry. His pioneering work helped found the modern theory of chemical affinity, chemical equilibrium, chemical kinetics, and chemical thermodynamics. In his 1874 pamphlet Van 't Hoff formulated the theory of the tetrahedral carbon atom and laid the foundations of stereochemistry. In 1875, he predicted the correct structures of allenes and cumulenes as well as their axial chirality. He is also widely considered one of the founders of physical chemistry as the discipline is known today.

Karen Mulder is a Dutch model and singer. She is well known for her work with Versace, Dior, and Chanel as a supermodel during the 1990s. Mulder repeatedly was featured on the cover of Vogue and was also a Victoria's Secret model. In the early 2000s, she began to speak out about the dark side of the modeling industry and the dangers faced by underage girls and young women.

Cees Nooteboom is a Dutch novelist, poet and journalist. After the attention received by his novel Rituelen, which received the Pegasus Prize, it was the first of his novels to be translated into an English edition, published in 1983 by Louisiana State University Press of the United States. LSU Press published his first two novels in English in the following years, as well as other works through 1990. Harcourt and Grove Press have since published some of his works in English.

Anner Bylsma was a Dutch cellist who played on both modern and period instruments in a historically informed style. He took an interest in music from an early age. He studied with Carel van Leeuwen Boomkamp at the Royal Conservatory of The Hague and won the Prix d'excellence in 1957.

Mathilde Hubertine Maria Francisca "Til" Gardeniers-Berendsen was a Dutch politician of the defunct Catholic People's Party (KVP) and later the Christian Democratic Appeal (CDA) party and nonprofit director.

Taco van der Hoorn is a Dutch cyclist who currently rides for UCI WorldTeam Intermarché–Wanty–Gobert Matériaux.

Raphael Guillermo Eduardo Maitimo is an Indonesian professional footballer who plays for Liga 1 club Persita Tangerang as a central midfielder, attacking midfielder or centre-forward, but he was used as an emergency centre-back. Maitimo was born and raised in the Netherlands. He is of Minangkabau descent.

Frederick Henry was the sovereign prince of Orange and stadtholder of Holland, Zeeland, Utrecht, Guelders, Overijssel in the Dutch Republic from 1625 until his death in 1647. The last seven years of his life he also was the stadtholder of Groningen (1640-1647).

Jan Joosten van Lodensteyn, known in Japanese as Yayōsu (耶楊子), was a native of Delft and one of the first Dutchmen in Japan, and the second mate on the Dutch ship De Liefde, which was stranded in Japan in 1600. Some of his shipmates were Jacob Quaeckernaeck, Melchior van Santvoort, and William Adams.