List of Famous people born in South Dakota, United States of America

Kathryn Uhrich is Dean of the College of Natural and Agricultural Sciences, at The University of California, Riverside, and founder of Polymerix Corporation. She has received many awards for her research and work including the ACS Buck-Whitney Award and the Sioux Award. She was a fellow at both the National Academy of Inventors and the American Chemical Socieyt in 2014.

Larry Lee Pressler is an American politician from South Dakota who served in the United States House of Representatives and United States Senate as a Republican. He remained active in politics following his failed reelection campaign in 1996 and attempted to regain his former seat in 2014 as an independent, but was unsuccessful.

Monte Cook is an American professional tabletop role-playing game designer and writer, best known for his work on Dungeons & Dragons.

Mary Candace Hilligoss is an American actress and former model. She gained fame for her role as Mary Henry in the independent horror film Carnival of Souls (1962).

Dennis Martin Daugaard is an American attorney and politician who served as the 32nd governor of South Dakota from 2011 to 2019. A member of the Republican Party, he was the first chief executive of a U.S. state to be the child of deaf parents. Before being elected governor, he was a lawyer, banker, development director for a nonprofit organization; he also served as a state senator from 1997 to 2003 and the 37th lieutenant governor of South Dakota from 2003 to 2011.

Dustin M. Johnson is an American politician serving as the U.S. Representative for South Dakota's at-large congressional district since 2019. A member of the Republican Party, he previously served as a South Dakota Public Utilities Commissioner from 2005 to 2011, when he was appointed chief of staff to Governor Dennis Daugaard, a position he retained until 2014. Between his state political career and congressional service, Johnson was the vice president of Vantage Point Solutions in Mitchell, South Dakota.

George Theodore Mickelson was an American attorney, 16th Attorney General and 18th Governor of South Dakota, and a United States District Judge of the United States District Court for the District of South Dakota. He is the patriarch of the prominent Mickelson family of South Dakota.

Harvey Lowell Wollman is an American politician who was the 26th Governor of South Dakota. He was the first Lieutenant Governor in the history of South Dakota to succeed to the governorship. He is the last Democrat to serve as South Dakota governor.

Timothy Peter Johnson is a retired American politician who served as a United States Senator from South Dakota from 1997 to 2015. A member of the Democratic Party, he previously served as the United States Representative for South Dakota's at-large congressional district from 1987 to 1997 and in the state legislature from 1979 to 1987. Johnson chose not to seek reelection in 2014. As of 2021, he is the last Democrat to hold statewide office in South Dakota.

Marion Michael Rounds is an American businessman and politician serving as the junior United States Senator from South Dakota since 2015. A member of the Republican Party, he served as the 31st governor of South Dakota from 2003 to 2011, and in the South Dakota Senate from 1991 to 2001.