List of Famous people born in São Tomé Province, São Tomé and Príncipe

Nuno Herlander Simões Espírito Santo, known simply as Nuno as a player, is a Portuguese former footballer who played as a goalkeeper, and is the current head coach of Premier League club Wolverhampton Wanderers.

Gedson Carvalho Fernandes is a Portuguese professional footballer who plays as a midfielder for Premier League club Tottenham Hotspur, on loan from Benfica, and the Portugal national team.

Enezaide do Rosário da Vera Cruz Gomes OIH is a former Portuguese heptathlete and long jumper. She also competed in 100 metres hurdles at the 2000 Summer Olympics. At club level, she represented Sporting CP.

Norberto José d'Alva Costa Alegre is a former prime minister of São Tomé and Príncipe. He held the post from 16 May 1992 to 2 July 1994. He is a member of the Democratic Convergence Party-Reflection Group (PCD-GR) and is married to former foreign minister Alda Bandeira.

Miguel dos Anjos da Cunha Lisboa Trovoada was Prime Minister (1975–1979) and President (1991–2001) of São Tomé and Príncipe. On 16 July 2014, he was appointed the Special Representative of the United Nations Secretary-General and Head of the United Nations Integrated Peacebuilding Office in Guinea-Bissau (UNIOGBIS). Prior to this, he was the Executive Secretary of the Gulf of Guinea Commission.

Olinda Beja is a São Tomé and Príncipe poet, writer and narrator. Later she immigrated to Portugal and moved to Viseu and later became a Portuguese citizen.

Manuel Pinto da Costa is a Santoméan economist and politician who served as the first President of São Tomé and Príncipe from 1975 to 1991. He again served as president from 2011 to 2016.

Maria da Conceição de Deus Lima, also known as Conceição Lima, is a Santomean poet.

Leonel Mário d'Alva is a São Toméan politician. He served as Prime Minister of São Tomé and Príncipe from 21 December 1974 until 12 July 1975, when the country gained independence from Portugal.

Francisco José Tenreiro was a São Toméan geographer and poet who lived during the colonial era. He was taught at the Overseas Political and Social Sciences Institute, now known as the Instituto Superior de Ciências Sociais e Políticas of the University of Lisbon.