List of Famous people born in Santiago Metropolitan Region, Chile

Francisco Javier Prado Aránguiz was a Chilean Roman Catholic bishop.

Jorge Máximo Arturo Pacheco Matte is a Chilean economist and politician. He served as minister of Michelle Bachelet's second government (2014−2018), specifically in Energy.

Alfredo Jaar is a Chilean-born artist, architect, photographer and filmmaker who lives in New York City. He is mostly known as an installation artist, often incorporating photography and covering socio-political issues and war—the best known perhaps being the 6-year-long The Rwanda Project about the 1994 Rwandan genocide. He has also made numerous public intervention works, like The Skoghall Konsthall one-day paper museum in Sweden, an early electronic billboard intervention A Logo For America, and The Cloud, a performance project on both sides of the Mexico-USA border. He has been featured on Art:21. He won the Hasselblad Award for 2020.

Francisco Javier Errázuriz Ossa is a Chilean prelate of the Catholic Church who served as Archbishop of Santiago from 1998 to 2010. He has been a cardinal since 2001 and was a member of Pope Francis' Council of Cardinal Advisers from its creation in 2013 until his departure in 2018.

Víctor Claudio José Pérez Varela is a Chilean lawyer and politician. He was Minister of Defense during the second government of the President Sebastián Piñera (2018–2022).