List of Famous people born in Plzeň, Czech Republic

Petr Čech is a Czech professional footballer who currently has a combined role of a technical/performance advisor and an emergency goalkeeper for English club Chelsea. He also played semi-professional ice hockey as a goaltender for Guildford Phoenix. Described by numerous players, pundits and managers as one of the greatest goalkeepers in European history, he is argued, alongside Peter Schmeichel, to be the greatest goalkeeper in Premier League history.

Barbora Strýcová, formerly known as Barbora Záhlavová-Strýcová, is a Czech professional tennis player. Her highest WTA rankings are world No. 16 in singles and No. 1 in doubles. Her best singles and doubles Grand Slam performances both came at the 2019 Wimbledon Championships, where she reached the singles semifinals and won the women's doubles title alongside Hsieh Su-wei.

Karel Gott was a Czech singer and amateur painter, considered the most successful male singer in Czechoslovakia and the Czech Republic. He was voted the country's best male singer in the annual Český slavík national music award 42 times, most recently in 2017.

Jan Kohout is a Czech diplomat and politician. He was Minister of Foreign Affairs of the Czech Republic in caretaker governments of Jan Fischer and Jiří Rusnok. Between 1986–1989 he had been a member of the Communist Party of Czechoslovakia; since 1995 is a member of the Social Democratic Party but before accepting the office of Foreign Minister he suspended party membership.

David Hirsch, known as Wolfgang Heinz, was an Austrian and East German actor and theater director. He served as President of the Academy of the Arts in Berlin between 1968 and 1974.

Kamil Krofta was a Czech historian and diplomat.

Emil Lederer was a Bohemian-born German economist and sociologist. Purged from his position at Humboldt University of Berlin in 1933 for being Jewish, Lederer fled into exile. He helped establish the "University in Exile" at the New School in New York City.

Gertrud Fussenegger was an Austrian writer and a prolific author, especially of historical novels. Many commentators felt that her reputation never entirely escaped from the shadow cast by her enthusiasm, as a young woman, for National Socialism.

Joseph Škoda was a Czech physician, medical professor and dermatologist. Together with Carl Freiherr von Rokitansky, he was the founder of the Modern Medical School of Vienna.

Jiří Trnka was a Czech puppet-maker, illustrator, motion-picture animator and film director.